The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs, Volume II

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ORIGINAL RESEARCH

Published on 16 Aug 2021

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

  • Mahmoud E. Youssef
  • Eslam E. Abd El-Fattah
  • Amir M. Abdelhamid
  • Hanan Eissa
  • Eman El-Ahwany
  • Noha A. Amin
  • Helal F. Hetta
  • Mohamed H. Mahmoud
  • Gaber El-Saber Batiha
  • 2 more
  • Sameh Saber
Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis
doi 10.3389/fphar.2021.719984
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  • 39 citations