Frontiers | The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs, Volume II

The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs, Volume II

6,563
Total downloads
25k
Total views and downloads

Articles

REVIEW

Published on 01 Jun 2022

Revisiting Preclinical Observations of Several Histamine H3 Receptor Antagonists/Inverse Agonists in Cognitive Impairment, Anxiety, Depression, and Sleep–Wake Cycle Disorder

Mera Alhusaini
Nermin Eissa
Ali K. Saad
Rami Beiram
Bassem Sadek

Revisiting Preclinical Observations of Several Histamine H3 Receptor Antagonists/Inverse Agonists in Cognitive Impairment, Anxiety, Depression, and Sleep–Wake Cycle Disorder

doi 10.3389/fphar.2022.861094

5,938 views
24 citations

ORIGINAL RESEARCH

Published on 31 Mar 2022

Galanin Regulates Myocardial Mitochondrial ROS Homeostasis and Hypertrophic Remodeling Through GalR2

Frederic Boal
Mathieu Cinato
Andrei Timotin
Heike Münzberg
Emily Qualls-Creekmore
Solomiia Kramar
Halyna Loi
Jerome Roncalli
Sokhna Keita
1 more
Oksana Kunduzova

Galanin Regulates Myocardial Mitochondrial ROS Homeostasis and Hypertrophic Remodeling Through GalR2

doi 10.3389/fphar.2022.869179

1,944 views
8 citations

ORIGINAL RESEARCH

Published on 08 Mar 2022

Votucalis, a Novel Centrally Sparing Histamine-Binding Protein, Attenuates Histaminergic Itch and Neuropathic Pain in Mice

Ibrahim Alrashdi
Amal Alsubaiyel
Michele Chan
Emma E. Battell
Abdel Ennaceur
Miles A. Nunn
Wayne Weston-Davies
Paul L. Chazot
Ilona Obara

Votucalis, a Novel Centrally Sparing Histamine-Binding Protein, Attenuates Histaminergic Itch and Neuropathic Pain in Mice

doi 10.3389/fphar.2022.846683

5,314 views
1 citation

REVIEW

Published on 21 Jan 2022

Decoupling Oxygen Tension From Retinal Vascularization as a New Perspective for Management of Retinopathy of Prematurity. New Opportunities From β-adrenoceptors

Luca Filippi
Maurizio Cammalleri
Rosario Amato
Massimiliano Ciantelli
Alessandro Pini
Paola Bagnoli
Massimo Dal Monte

Decoupling Oxygen Tension From Retinal Vascularization as a New Perspective for Management of Retinopathy of Prematurity. New Opportunities From β-adrenoceptors

doi 10.3389/fphar.2022.835771

2,071 views
23 citations

ORIGINAL RESEARCH

Published on 16 Aug 2021

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Mahmoud E. Youssef
Eslam E. Abd El-Fattah
Amir M. Abdelhamid
Hanan Eissa
Eman El-Ahwany
Noha A. Amin
Helal F. Hetta
Mohamed H. Mahmoud
Gaber El-Saber Batiha
2 more
Sameh Saber

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

doi 10.3389/fphar.2021.719984

6,686 views
40 citations

Share on

Frontiers in Pharmacology

Frontiers in Pharmacology

Experimental Pharmacology and Drug Discovery

Impact

25kTopic views
18kArticle views
6,563Article downloads