Advances in Brain Tumors Diagnosis and Treatment

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Editorial

04 May 2023

Editorial: Advances in brain tumors diagnosis and treatment

Dario de Biase

,

Enrico Franceschi

and

Gianluca Marucci

1,994 views

3 citations

Editors

3

Dario de Biase

University of Bologna

Enrico Franceschi

IRCCS Institute of Neurological Sciences of Bologna (ISNB)

Gianluca Marucci

IRCCS Carlo Besta Neurological Institute Foundation

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The 2016 World Health Organization (WHO) classification had provided molecular characterization a central role in glioma classification. Significant improvements have been performed in characterizing brain tumors to predict survival outcomes and treatment response. Novel therapeutic approaches, based on cancer biology, are increasingly being used, with promising results on tumor outcome. Despite progress in surgical techniques, molecular characterization, and “target therapy”, prognosis of malignant gliomas remains usually poor and they still lacks effective treatments. This evidence indicates a need for precise parameters to further classifying brain tumors. Our understanding of the molecular pathology of brain tumors has progressed significantly, bringing many benefits in this respect. However, it is necessary to continue this research for more personalized diagnoses and novel therapeutic approaches. Advanced diagnostic strategies may help to better classify brain neoplastic entities and to predict their biological behavior, as prognosis or response to therapy.

The focus of this Research Topic is on the application of novel discovery in characterizing brain tumors for diagnostic, prognostic, or predictive purposes. It is dedicated to answering unsolved diagnostic and biological questions in brain tumors focusing on novel/advanced strategies in imaging, histological, genetic, and molecular analysis and the potential applications of these strategies at bedside. Researchers are encouraged to submit original research articles on the application of novel/advanced techniques in the characterization of brain tumors. Original research and review articles describing the state of the art and systematic reviews on this topic are also encouraged, as well as work in the following areas:

• Brain tumors

• Gliomas

• Brain tumors diagnosis

• Molecular pathology of brain tumors

• microRNA

• Target therapy

• Therapeutic approach in brain tumors

The 2016 World Health Organization (WHO) classification had provided molecular characterization a central role in glioma classification. Significant improvements have been performed in characterizing brain tumors to predict survival outcomes and treatment response. Novel therapeutic approaches, based on cancer biology, are increasingly being used, with promising results on tumor outcome. Despite progress in surgical techniques, molecular characterization, and “target therapy”, prognosis of malignant gliomas remains usually poor and they still lacks effective treatments. This evidence indicates a need for precise parameters to further classifying brain tumors. Our understanding of the molecular pathology of brain tumors has progressed significantly, bringing many benefits in this respect. However, it is necessary to continue this research for more personalized diagnoses and novel therapeutic approaches. Advanced diagnostic strategies may help to better classify brain neoplastic entities and to predict their biological behavior, as prognosis or response to therapy.

The focus of this Research Topic is on the application of novel discovery in characterizing brain tumors for diagnostic, prognostic, or predictive purposes. It is dedicated to answering unsolved diagnostic and biological questions in brain tumors focusing on novel/advanced strategies in imaging, histological, genetic, and molecular analysis and the potential applications of these strategies at bedside. Researchers are encouraged to submit original research articles on the application of novel/advanced techniques in the characterization of brain tumors. Original research and review articles describing the state of the art and systematic reviews on this topic are also encouraged, as well as work in the following areas:

• Brain tumors

• Gliomas

• Brain tumors diagnosis

• Molecular pathology of brain tumors

• microRNA

• Target therapy

• Therapeutic approach in brain tumors

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Editors

Dario de Biase

University of Bologna

Enrico Franceschi

IRCCS Institute of Neurological Sciences of Bologna (ISNB)

Gianluca Marucci

IRCCS Carlo Besta Neurological Institute Foundation

Impact

86,559 Total views

57,066 Article views

28,047 Article downloads

1,446 Topic views

Published In

Frontiers in Medicine

Pathology

Frontiers in Neurology

Neuro-Oncology and Neurosurgical Oncology

Frontiers in Oncology

Neuro-Oncology and Neurosurgical Oncology

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