Despite vast scientific interest, molecular mechanisms underlying neural stem cell self-renewal and neurogenesis remain elusive. Recently, microRNAs emerged as central players in neural stem cell self-renewal and differentiation. . This Research Topic will focus on how microRNAs, through their interactions with other components of the regulatory network, control the self-renewal and differentiation of neural stem cells. Deciphering such a mechanism will not only provide insights into basic neurosciences but also facilitate clinical applications of stem cell-based therapies for neurodegenerative diseases.
Despite vast scientific interest, molecular mechanisms underlying neural stem cell self-renewal and neurogenesis remain elusive. Recently, microRNAs emerged as central players in neural stem cell self-renewal and differentiation. . This Research Topic will focus on how microRNAs, through their interactions with other components of the regulatory network, control the self-renewal and differentiation of neural stem cells. Deciphering such a mechanism will not only provide insights into basic neurosciences but also facilitate clinical applications of stem cell-based therapies for neurodegenerative diseases.