Gastric cancer is one of five common cancers worldwide. The majority of the patients with advanced-stage gastric cancers have dismal prognoses. Multimodal management of locally-advanced gastric cancers have improved the survival outcomes. However, there is still not sufficient data to how multiple modalities can be combined and sequenced – total neoadjuvant vs. perioperative vs. adjuvant, or chemotherapy vs. chemoradiotherapy vs. radiotherapy. The role of targeted therapy is also emerging in the management of locally advanced gastric cancer.
Moreover, there are various technical issues that are controversial in the surgical management of gastric cancer. The surgical principles and techniques (extent of lymphadenectomy, bursectomy, omentectomy, etc.) vary significantly across centres worldwide. The oncological outcomes of minimally invasive surgery are still not well-defined. The identification of malignant cells in peritoneal washings in the absence of obvious metastasis is another area of research – should these patients be treated with a curative intent. This question has become more relevant due to the rapid progress in the field of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
We aim to collect manuscripts focusing on various aspects of the multimodal management of locally advanced gastric cancer. We are particularly interested in:
o Conflicting surgical strategies
o Minimally invasive surgical techniques
o Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
o Perioperative chemotherapy protocols
o Management of isolated locoregional recurrence
Gastric cancer is one of five common cancers worldwide. The majority of the patients with advanced-stage gastric cancers have dismal prognoses. Multimodal management of locally-advanced gastric cancers have improved the survival outcomes. However, there is still not sufficient data to how multiple modalities can be combined and sequenced – total neoadjuvant vs. perioperative vs. adjuvant, or chemotherapy vs. chemoradiotherapy vs. radiotherapy. The role of targeted therapy is also emerging in the management of locally advanced gastric cancer.
Moreover, there are various technical issues that are controversial in the surgical management of gastric cancer. The surgical principles and techniques (extent of lymphadenectomy, bursectomy, omentectomy, etc.) vary significantly across centres worldwide. The oncological outcomes of minimally invasive surgery are still not well-defined. The identification of malignant cells in peritoneal washings in the absence of obvious metastasis is another area of research – should these patients be treated with a curative intent. This question has become more relevant due to the rapid progress in the field of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
We aim to collect manuscripts focusing on various aspects of the multimodal management of locally advanced gastric cancer. We are particularly interested in:
o Conflicting surgical strategies
o Minimally invasive surgical techniques
o Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
o Perioperative chemotherapy protocols
o Management of isolated locoregional recurrence