About this Research Topic
In this Research Topic, we want to focus on the different components of the immune system that can potentially influence the cardiovascular remodeling process. We want to better understand how we can use parts of the immune system as biomarkers, but also in particular in which phase of the disease they might be helpful. In addition, it is important how new insights such as gender differences and the influence of the microbiome may play a role. We also find it important to look for new therapies or strategies that exert their work through immunomodulation but also how antibody therapies used against e.g. cancer cause harm to the heart.
We are looking for interesting pilot data, novel research papers (preclinical as well as clinical) or reviews on the role of inflammation and (potential) immunomodulation strategies in cardiovascular remodeling processes such as atherosclerosis, heart failure and cardiotoxicity/myocarditis. This can be, for example, the process of atherosclerotic plaque formation, but also remodeling after a heart attack or the pathophysiological process within heart failure with preserved ejection fraction (HFpEF) or myocarditis during cancer treatment with antibody therapy. We are also happy to consider submission on a diseases such as stroke or aneurysm. We believe it is important to pay attention to themes such as gender differences or the role of the microbiome, but this is not a specific requirement.
Keywords: Inflammation, remodeling, atherosclerosis, heart failure, immunomodulation
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