About this Research Topic
The literature in the past decade has been overwhelmed with studies debating the existence of a link between traumatic brain injury and Alzheimer’s or non-Alzheimer’s degenerative diseases. While a number of studies have shown a link with Alzheimer’s, other studies have shown a relationship with non-typical Alzheimer’s disease or Parkinson’s disease. This Research Topic aims to eradicate this dilemma by bringing together multimodality data, including longitudinal, preclinical and postmortem studies for an evidence-based approach to the real relationship between traumatic brain injury and neurodegenerative diseases.
The Research Topic aims to shed more clarification on whether TBI-induced processes in the brain are linked with long-term development of dementia and neurodegenerative diseases. The topic will include:
- Longitudinal progression of brain changes following traumatic brain injury.
- Neuroimaging and machine learning approaches to predict the link with dementias
- Preclinical and postmortem studies of traumatic brain injury.
- Repetitive trauma and chronic traumatic encephalopathy
Keywords: Traumatic brain injury, Neuroimaging, Neuroinflammation, Alzheimers, Neurofibrillary tau tangles, Amyloid plaques
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.