In physiological conditions, complex regulatory pathways maintain gastrointestinal (GI) homeostasis in a healthy intestinal tract; however, defects in any of these mechanisms can favor the establishment of a pathological process, resulting in the development of GI injuries and disturbances, or functional GI disorders, such as Crohn's disease, ulcerative colitis, functional dyspepsia, or irritable bowel syndrome, as well as systemic disorders. These conditions represent a significant need for conventional medical treatment, particularly because long term use of these drugs reduces their efficacy and is commonly accompanied by side effects.
In this sense, nutrients from the diet not only provide the necessary basis for energy and body growth and repair, but also impacts and regulates several important physiological functions. Additionally, it is increasingly recognized that dietary nutrients, including probiotics, prebiotics, carbohydrates, proteins, among others, may affect GI homeostasis, by influencing intestinal cells, immune system and the gut microbiota, and may therefore be effective in treating GI diseases.
This Research Topic will contribute to an increased understanding of how dietary nutrients can contribute to GI homeostasis and the treatment of related diseases. The knowledge could be applied in translational studies. Our goal is to provide an up-to-date overview of the progress in our knowledge regarding the role of dietary nutrients in GI homeostasis, and how it can contribute during a pathological process.
In this Research Topic we welcome original articles, mini-reviews, reviews, commentaries, and perspectives. Manuscripts must focus on any aspects of:
- Nutrition or nutrients from diet and regulation of GI homeostasis;
- Nutrition or nutrients from diet and regulation of GI injuries and disturbances;
- Nutrition or nutrients from diet as treatment of GI injuries and disturbances or correlated disorders.
In physiological conditions, complex regulatory pathways maintain gastrointestinal (GI) homeostasis in a healthy intestinal tract; however, defects in any of these mechanisms can favor the establishment of a pathological process, resulting in the development of GI injuries and disturbances, or functional GI disorders, such as Crohn's disease, ulcerative colitis, functional dyspepsia, or irritable bowel syndrome, as well as systemic disorders. These conditions represent a significant need for conventional medical treatment, particularly because long term use of these drugs reduces their efficacy and is commonly accompanied by side effects.
In this sense, nutrients from the diet not only provide the necessary basis for energy and body growth and repair, but also impacts and regulates several important physiological functions. Additionally, it is increasingly recognized that dietary nutrients, including probiotics, prebiotics, carbohydrates, proteins, among others, may affect GI homeostasis, by influencing intestinal cells, immune system and the gut microbiota, and may therefore be effective in treating GI diseases.
This Research Topic will contribute to an increased understanding of how dietary nutrients can contribute to GI homeostasis and the treatment of related diseases. The knowledge could be applied in translational studies. Our goal is to provide an up-to-date overview of the progress in our knowledge regarding the role of dietary nutrients in GI homeostasis, and how it can contribute during a pathological process.
In this Research Topic we welcome original articles, mini-reviews, reviews, commentaries, and perspectives. Manuscripts must focus on any aspects of:
- Nutrition or nutrients from diet and regulation of GI homeostasis;
- Nutrition or nutrients from diet and regulation of GI injuries and disturbances;
- Nutrition or nutrients from diet as treatment of GI injuries and disturbances or correlated disorders.
