About this Research Topic
Eukaryotic gene expression results from far more than the linear code depicted by DNA sequence. Accounting for the phenomena is the fact that a multitude of integrated factors shape genome organization and function. The genome is packaged into chromatin and enclosed within a confined cellular space termed the nucleus. Chromatin structure is driven, at least in part, by epigenetic modifications, such as DNA methylation and histone post-translations modifications, that do not alter the primary sequence of DNA but impose an additional layer in gene expression regulation. On the other hand, proteins and RNA organize in distinct, membraneless nuclear bodies where specific nuclear processes occur. These multiple levels of nuclear organization along with epigenetic modifications come together to allow proper gene transcription and DNA replication and are an important part of the cellular response to external and internal stimuli. In this topic, all types of articles that shed a light on the subject of epigenetics and nuclear organization in plants are welcomed. We will consider contributions that define the formation, dynamics and mode-of-action of the several mechanisms underlying the establishment of epigenetic modifications and nuclear organization, overlap between the different levels of nuclear organization and how those intersect in plant development and signaling.
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