Frontiers | Application of Next Generation Sequencing (NGS) and CRISPR-Cas Systems in The Diagnosis of Infectious Diseases

Application of Next Generation Sequencing (NGS) and CRISPR-Cas Systems in The Diagnosis of Infectious Diseases

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REVIEW

Published on 13 Jul 2022

Potential Opportunities and Challenges of Deploying Next Generation Sequencing and CRISPR-Cas Systems to Support Diagnostics and Surveillance Towards Malaria Control and Elimination in Africa

Beatus M. Lyimo
Zachary R. Popkin-Hall
David J. Giesbrecht
Celine I. Mandara
Rashid A. Madebe
Catherine Bakari
Dativa Pereus
Misago D. Seth
Ramadhan M. Ngamba
14 more
Deus S. Ishengoma

doi 10.3389/fcimb.2022.757844

4,247 views
15 citations

CASE REPORT

Published on 18 Apr 2022

Case Report: An Ulceration With a Stalactite Appearance on the Index Finger

Liangliang Zhang
Yalan Dai
Mengting Lin
Qiuyun Xu
Tingting Lin
Ting Gong
Bo Cheng
Chao Ji
Donghua Cai

doi 10.3389/fmed.2022.801086

2,099 views

CASE REPORT

Published on 12 Apr 2022

Multisystem Involvement Induced by Human Parvovirus B19 Infection in a Non-immunosuppressed Adult: A Case Report

Qihang Zou
Peisong Chen
Jiaxin Chen
Dingbang Chen
Han Xia
Ling Chen
Huiyu Feng
Li Feng

doi 10.3389/fmed.2022.808205

7,718 views
4 citations

CASE REPORT

Published on 08 Apr 2022

Recurrent Pneumonia With Tuberculosis and Candida Co-infection Diagnosed by Metagenomic Next-Generation Sequencing: A Case Report and Literature Review

Ning Ma
Mei Chen
Jingyi Ding
Fang Wang
Jingbo Jin
Sitong Fan
Jiajia Chen

doi 10.3389/fmed.2022.755308

3,902 views
4 citations

ORIGINAL RESEARCH

Published on 24 Mar 2022

Invasive Pulmonary Aspergillosis Diagnosis via Peripheral Blood Metagenomic Next-Generation Sequencing

Xiaoxu Ma
Suping Zhang
Haizhou Xing
Huiling Li
Jiajun Chen
Haijun Li
Mengfan Jiao
Qingmiao Shi
Aiguo Xu
1 more
Weijie Cao

doi 10.3389/fmed.2022.751617

4,652 views
18 citations

ORIGINAL RESEARCH

Published on 03 Mar 2022

Characteristics and Prognostic Factors of Non-HIV Immunocompromised Patients With Pneumocystis Pneumonia Diagnosed by Metagenomics Next-Generation Sequencing

Jiali Duan
Jing Gao
Qiuhong Liu
Mengfei Sun
Yang Liu
Yingshuai Tan
Lihua Xing

doi 10.3389/fmed.2022.812698

2,467 views
15 citations

CASE REPORT

Published on 16 Feb 2022

Brain Abscess Caused by Nocardia farcinica and Diagnosed by Metagenomic Next-Generation Sequencing: A Case Report

Jianhua Yang
Shuhua Xie
Junda Li
Han Xia
Xianghong Liu

doi 10.3389/fmed.2022.803554

3,872 views
7 citations

CASE REPORT

Published on 14 Feb 2022

Autoimmune Encephalitis With Multiple Auto-Antibodies With Concomitant Human Herpesvirus-7 and Ovarian Teratoma: A Case Report

Jianhua Yang
Pengcheng Wu
Xianghong Liu
Han Xia
Zhaohui Lai

doi 10.3389/fmed.2021.759559

3,217 views
8 citations

CASE REPORT

Published on 28 Jan 2022

Case Report: Community-Acquired Legionella gormanii Pneumonia in an Immunocompetent Patient Detected by Metagenomic Next-Generation Sequencing

Cheng Lei
Xianglin Zhou
Shuizi Ding
Yingjie Xu
Binyi Yang
Wei Guo
Min Song
Min Yang
Yunan Jia
Hong Luo

doi 10.3389/fmed.2022.819425

3,777 views
10 citations

CASE REPORT

Published on 25 Jan 2022

Next Generation Sequencing for Diagnosis of Leptospirosis Combined With Multiple Organ Failure: A Case Report and Literature Review

Juan Lu
Juan Hu
Shanshan Yu
Lanjuan Li

doi 10.3389/fmed.2021.756592

2,264 views
6 citations

ORIGINAL RESEARCH

Published on 21 Jan 2022

Evaluations of Clinical Utilization of Metagenomic Next-Generation Sequencing in Adults With Fever of Unknown Origin

Zhang-fan Fu
Hao-cheng Zhang
Yi Zhang
Peng Cui
Yang Zhou
Hong-yu Wang
Ke Lin
Xian Zhou
Jing Wu
2 more
Jing-wen Ai

doi 10.3389/fcimb.2021.745156

4,955 views
20 citations

ORIGINAL RESEARCH

Published on 21 Jan 2022

Metagenomic Next-Generation Sequencing vs. Traditional Microbiological Tests for Diagnosing Varicella-Zoster Virus Central Nervous System Infection

Yunqi Zhu
Miaomiao Xu
Chengyuan Ding
Zhihang Peng
Weixiao Wang
Binghu Sun
Jian Cheng
Chen Chen
Wei Chen
1 more
Zhiliang Hu

doi 10.3389/fpubh.2021.738412

3,249 views
13 citations

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Clinical Microbiology

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- Infectious Diseases – Surveillance, Prevention and TreatmentOffline
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Articles

Potential Opportunities and Challenges of Deploying Next Generation Sequencing and CRISPR-Cas Systems to Support Diagnostics and Surveillance Towards Malaria Control and Elimination in Africa

Case Report: An Ulceration With a Stalactite Appearance on the Index Finger

Multisystem Involvement Induced by Human Parvovirus B19 Infection in a Non-immunosuppressed Adult: A Case Report

Recurrent Pneumonia With Tuberculosis and Candida Co-infection Diagnosed by Metagenomic Next-Generation Sequencing: A Case Report and Literature Review

Invasive Pulmonary Aspergillosis Diagnosis via Peripheral Blood Metagenomic Next-Generation Sequencing

Characteristics and Prognostic Factors of Non-HIV Immunocompromised Patients With Pneumocystis Pneumonia Diagnosed by Metagenomics Next-Generation Sequencing

Brain Abscess Caused by Nocardia farcinica and Diagnosed by Metagenomic Next-Generation Sequencing: A Case Report

Autoimmune Encephalitis With Multiple Auto-Antibodies With Concomitant Human Herpesvirus-7 and Ovarian Teratoma: A Case Report

Case Report: Community-Acquired Legionella gormanii Pneumonia in an Immunocompetent Patient Detected by Metagenomic Next-Generation Sequencing

Next Generation Sequencing for Diagnosis of Leptospirosis Combined With Multiple Organ Failure: A Case Report and Literature Review

Evaluations of Clinical Utilization of Metagenomic Next-Generation Sequencing in Adults With Fever of Unknown Origin

Metagenomic Next-Generation Sequencing vs. Traditional Microbiological Tests for Diagnosing Varicella-Zoster Virus Central Nervous System Infection

Frontiers in Cellular and Infection Microbiology

Participating Journals

Impact