Researchers in diverse fields dissect elements in genomes with various genomic methods. It has been approximately 30 years since the initiation of human genome project. Three generations of sequencing technology have been established and successfully applied. First generation sequencing almost exclusively served model organisms. Second generation sequencing largely improved the throughput and decreased the cost. Coupled with algorithm development, it promoted the release of hundreds and thousands of genomes, which have been the foundation of the research boom in evolution and genetics in the past decade. Recent developments of third generation sequencing allow long reads to be produced at an acceptable cost. Together with long-range interacting information, such as Hi-C sequencing, chromosome-level genome assembly can be easily achieved. The increasing release of complete genome assemblies promotes the dissection of genotype-phenotype interactions and deepens our understanding of phylogeny and evolution, especially for non-model species.
The main objective of this Research Topic is to provide a forum to communicate recent research on high-quality genome assembly for fishery and aquaculture species, including the successful and not-so-successful cases. The consensus sequence of the assembly should be provided, and haplotype-aware assemblies should be explored, such as those regions that contain sex-determination genes. Issues that hamper the assembly of a high-quality genome, such as super large genome size and high percentage of repeats, are also welcomed. Genomic insights for improving germplasm, conservation, and understanding the evolutionary history of exploited species are of interest.
We welcome the following subtopics: (1) exploration of genomes, (2) application of genomic information for dissecting the special phenotype and evolution, microevolution, or macroevolution, (3) review of sequencing technologies, (4) comparison of genome assemblers, and (5) the tools for improving or assessing assembly quality.
Researchers in diverse fields dissect elements in genomes with various genomic methods. It has been approximately 30 years since the initiation of human genome project. Three generations of sequencing technology have been established and successfully applied. First generation sequencing almost exclusively served model organisms. Second generation sequencing largely improved the throughput and decreased the cost. Coupled with algorithm development, it promoted the release of hundreds and thousands of genomes, which have been the foundation of the research boom in evolution and genetics in the past decade. Recent developments of third generation sequencing allow long reads to be produced at an acceptable cost. Together with long-range interacting information, such as Hi-C sequencing, chromosome-level genome assembly can be easily achieved. The increasing release of complete genome assemblies promotes the dissection of genotype-phenotype interactions and deepens our understanding of phylogeny and evolution, especially for non-model species.
The main objective of this Research Topic is to provide a forum to communicate recent research on high-quality genome assembly for fishery and aquaculture species, including the successful and not-so-successful cases. The consensus sequence of the assembly should be provided, and haplotype-aware assemblies should be explored, such as those regions that contain sex-determination genes. Issues that hamper the assembly of a high-quality genome, such as super large genome size and high percentage of repeats, are also welcomed. Genomic insights for improving germplasm, conservation, and understanding the evolutionary history of exploited species are of interest.
We welcome the following subtopics: (1) exploration of genomes, (2) application of genomic information for dissecting the special phenotype and evolution, microevolution, or macroevolution, (3) review of sequencing technologies, (4) comparison of genome assemblers, and (5) the tools for improving or assessing assembly quality.
