Genetics of Complex Traits & Diseases from Under-Represented Populations

48.9K

views

69

authors

11

articles

Genetics of Complex Traits & Diseases from Under-Represented Populations

48.9K

views

69

authors

11

articles

Editorial

17 January 2022

Editorial: Genetics of Complex Traits and Diseases From Under-Represented Populations

Segun Fatumo

,

Tinashe Chikowore

and

Karoline Kuchenbaecker

2,142 views

1 citations

Editors

3

Queen Mary University of London

Tinashe Chikowore

University of the Witwatersrand

Karoline Kuchenbaecker

University College London

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Our genes play a role in the occurrence of diseases and the characteristics of complex traits. An understanding of the interplay of these genes and environmental factors is essential for the development of effective therapeutic approaches for the management of diseases. Unfortunately, the majority of the genetic studies have been performed in Europeans. The underrepresentation of ethnically diverse populations hinders our ability to completely comprehend the genetic architecture of complex traits and human disease, thereby worsening health inequalities in the underrepresented populations.

In this Research Topic, we are seeking high-quality Original Research and Review papers describing the genetics of diseases in understudied populations. These include African, Latin American, Indian and other indigenous populations. The specific themes of interest in this special issue include but not limited to:
- Genome-wide association studies;
- Gene-environment interactions;
- Polygenic/Genetic Risk Scores;
- Epigenetics;
- Pharmacogenomics;
- Microbiome studies.

Our genes play a role in the occurrence of diseases and the characteristics of complex traits. An understanding of the interplay of these genes and environmental factors is essential for the development of effective therapeutic approaches for the management of diseases. Unfortunately, the majority of the genetic studies have been performed in Europeans. The underrepresentation of ethnically diverse populations hinders our ability to completely comprehend the genetic architecture of complex traits and human disease, thereby worsening health inequalities in the underrepresented populations.

In this Research Topic, we are seeking high-quality Original Research and Review papers describing the genetics of diseases in understudied populations. These include African, Latin American, Indian and other indigenous populations. The specific themes of interest in this special issue include but not limited to:
- Genome-wide association studies;
- Gene-environment interactions;
- Polygenic/Genetic Risk Scores;
- Epigenetics;
- Pharmacogenomics;
- Microbiome studies.

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Editors

Queen Mary University of London

Tinashe Chikowore

University of the Witwatersrand

Karoline Kuchenbaecker

University College London

Impact

48,930 Total views

35,972 Article views

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1,720 Topic views

Published In

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Frontiers in Genetics

Genetics of Common and Rare Diseases

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Frontiers in Pediatrics

Genetics of Common and Rare Diseases

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