About this Research Topic
The interface between biological tissues and biomaterials plays significant roles in wound healing, ranging from basic wound closure to the activation of biological pathways to achieve complete wound healing. Solid grounding in the mechanisms of the interface between tissues and biomaterials enables novel technologies for wound healing, including efficient healing strategies, new non-invasive wound closure methods, as well as advanced technology to reduce immune responses to biomaterials. Specifically, these measures may include the adhesion of tissues and biomaterials for rapid hemostasis, sealing and closure, and the impact of biological pathways on the recreation of instructive microenvironment or the reduction of foreign body reaction, fibrosis, giant cells and tissue damage caused by wound dressings. Novel scientific strategies optimizing the interaction between interfaces will improve patient care, which will enable us to treat wounds with fewer materials and less effort, while achieving a better outcome, thus bringing about significant economic benefits.
Novel interfacial strategies. Many chemical, physical and biological approaches are being explored to optimize interactions between tissues and biomaterials in wound healing. Bulk and surface properties of biomaterials can exert a great influence on their interaction with tissues, further affecting wound healing. In addition to topological optimization, many other methods have been developed for realizing proper interaction between materials and tissues including peptide-protein recognition, charge, mechanosensing as well as chemical interactions. Such advances as dopa chemistry, hierarchical architectures, and tuning of cell polarization and behavior are emerging technologies that regulate the biological-material interface.
Innovative applications of the interfacial strategies to improve wound healing. Non-invasive wound closure products (e.g., bioadhesives) are revolutionizing wound closure surgery. Manipulating interfacial properties, cell growth, proliferation, immigration, and differentiation allows us to achieve enhanced wound healing and tissue regeneration. Toward this end, we aim to tune the interfacial interactions to minimize the foreign body reactions, thereby attenuating scar formation. Meanwhile, there are many applications in wound healing that can be facilitated by employing different interfacial strategies, such as developing efficient wearable devices for wound care, fabricating functional coatings to prevent complications in wound healing, generating novel biomimetic materials and making specific drug delivery system.
Within this Research Topic, we aim to bring up to date the advances in biomaterials science and wound healing, and address the influence of interfacial strategies in wound healing. Submissions may include the development of novel tissue adhesives, discussions of cellular interactions, and predetermined biomaterial properties chosen to govern these interactions for optimal biomaterial performance.
• Development, discussion and enhancement of interface strategies between tissues and biomaterial.
• Application of interface strategies in biomedical applications including, tissue engineering, drug delivery, functional coating, wound closure, wearable and implantable devices, and so on.
Interested submissions include original research articles, and to a lesser degree General Commentaries, Review articles, Opinion articles, or Hypothesis and Theory articles.
We would like to acknowledge Dr. Yazhong Bu who has acted as coordinator and organized to the preparation of the proposal for this Research Topic.
Novel interfacial strategies. Many chemical, physical and biological approaches are being explored to optimize interactions between tissues and biomaterials in wound healing. Bulk and surface properties of biomaterials can exert a great influence on their interaction with tissues, further affecting wound healing. In addition to topological optimization, many other methods have been developed for realizing proper interaction between materials and tissues including peptide-protein recognition, charge, mechanosensing as well as chemical interactions. Such advances as dopa chemistry, hierarchical architectures, and tuning of cell polarization and behavior are emerging technologies that regulate the biological-material interface.
Innovative applications of the interfacial strategies to improve wound healing. Non-invasive wound closure products (e.g., bioadhesives) are revolutionizing wound closure surgery. Manipulating interfacial properties, cell growth, proliferation, immigration, and differentiation allows us to achieve enhanced wound healing and tissue regeneration. Toward this end, we aim to tune the interfacial interactions to minimize the foreign body reactions, thereby attenuating scar formation. Meanwhile, there are many applications in wound healing that can be facilitated by employing different interfacial strategies, such as developing efficient wearable devices for wound care, fabricating functional coatings to prevent complications in wound healing, generating novel biomimetic materials and making specific drug delivery system.
Within this Research Topic, we aim to bring up to date the advances in biomaterials science and wound healing, and address the influence of interfacial strategies in wound healing. Submissions may include the development of novel tissue adhesives, discussions of cellular interactions, and predetermined biomaterial properties chosen to govern these interactions for optimal biomaterial performance.
• Development, discussion and enhancement of interface strategies between tissues and biomaterial.
• Application of interface strategies in biomedical applications including, tissue engineering, drug delivery, functional coating, wound closure, wearable and implantable devices, and so on.
Interested submissions include original research articles, and to a lesser degree General Commentaries, Review articles, Opinion articles, or Hypothesis and Theory articles.
We would like to acknowledge Dr. Yazhong Bu who has acted as coordinator and organized to the preparation of the proposal for this Research Topic.
Keywords: Wound Healing, Interfacial Interaction, Tissue Adhesion
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
