Advanced Computational Intelligence Methods for Processing Brain Imaging Data

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Original Research
22 March 2022
Cross-Attention and Deep Supervision UNet for Lesion Segmentation of Chronic Stroke
Manjin Sheng
2 more and 
Zhongjie Chen
Comparisons of our method, baseline, FCN-8s, U-Net, ResUNet, and attention-UNet.

Stroke is an acute cerebrovascular disease with high incidence, high mortality, and high disability rate. Determining the location and volume of the disease in MR images promotes accurate stroke diagnosis and surgical planning. Therefore, the automatic recognition and segmentation of stroke lesions has important clinical significance for large-scale stroke imaging analysis. There are some problems in the segmentation of stroke lesions, such as imbalance of the front and back scenes, uncertainty of position, and unclear boundary. To meet this challenge, this paper proposes a cross-attention and deep supervision UNet (CADS-UNet) to segment chronic stroke lesions from T1-weighted MR images. Specifically, we propose a cross-spatial attention module, which is different from the usual self-attention module. The location information interactively selects encode features and decode features to enrich the lost spatial focus. At the same time, the channel attention mechanism is used to screen the channel characteristics. Finally, combined with deep supervision and mixed loss, the model is supervised more accurately. We compared and verified the model on the authoritative open dataset “Anatomical Tracings of Lesions After Stroke” (Atlas), which fully proved the effectiveness of our model.

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Frontiers in Medicine

AI Innovations in Neuroimaging: Transforming Brain Analysis
Edited by S B Goyal, Deepti Deshwal, Pardeep Sangwan
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05 August 2025
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