RNA Modifications and Epitranscriptomics

222.7K

views

159

authors

30

articles

Editors

3

Xiao Han

Institute of Biotechnology, Chinese Academy of Agricultural Sciences

Jia Meng

Xi'an Jiaotong-Liverpool University

Giovanni Nigita

The Ohio State University

Impact

Fetching...

About

In recent years, RNA modification has led to exciting new findings in epigenetic research, attracting the best scientists globally. Numerous studies have demonstrated that among hundreds of modifications in RNA, RNA methylation and editing were the critical mechanisms underlying the epi-regulation of gene expression and protein translation. In particular, significant advances in methods for imaging and detailing characteristics of RNA methylation have also helped researchers understand RNA demethylases, methyltransferases, binding proteins, and their biological function during RNA methylation. For instance, studies revealed that RNA modifications, in general, play a critical role in cancer cell development. Furthermore, virus replication within the host cell is affected by the interference of RNA modifications. RNA modifications play a crucial role in a variety of organisms and responses, including animal cells, plant development, and stress responses.

In this Research Topic, we aim to gather articles from epi-transcriptomics studies on any form of life, including viruses, microbes, plants, and animals. Additionally, we will consider research that reveals the role of epitranscriptomics in multiple human diseases. We welcome Original Research, Brief Research Reports, and Review articles covering: RNA modification motifs, functions of modification systems, and also relevant discoveries on RNA modification phenomena in both coding and non-coding RNAs.

We are also interested in epitranscriptome bioinformatics, including but not limited to, in silico identification of RNA modification sites from primary sequences, novel computational approaches, and new software tools for analysis of high-throughput epitranscriptome profiling datasets, RNA modifications databases, and computational methods to predict RNA secondary structures and RNA interaction for modified RNA molecules.

Download ebook

PDF

EPUB

Share

Editors

Xiao Han

Institute of Biotechnology, Chinese Academy of Agricultural Sciences

Jia Meng

Xi'an Jiaotong-Liverpool University

Giovanni Nigita

The Ohio State University

Impact

222,732 Total views

152,456 Article views

67,356 Article downloads

2,920 Topic views

Published In

Frontiers in Genetics

Epigenomics and Epigenetics, RNA

Frontiers in Cell and Developmental Biology

Epigenomics and Epigenetics

Frontiers in Molecular Biosciences

RNA

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic