Frontiers | Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation

Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation

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ORIGINAL RESEARCH

Published on 15 Nov 2021

An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation

Sakshi Khurana
Stefano Schivo
Jacqueline R. M. Plass
Nikolas Mersinis
Jetse Scholma
Johan Kerkhofs
Leilei Zhong
Jaco van de Pol
Rom Langerak
2 more
Janine N. Post

doi 10.3389/fbioe.2021.732917

2,007 views
3 citations

METHODS

Published on 10 Nov 2021

Evidence-Based Network Modelling to Simulate Nucleus Pulposus Multicellular Activity in Different Nutritional and Pro-Inflammatory Environments

L. Baumgartner
A. Sadowska
L. Tío
M. A. González Ballester
K. Wuertz-Kozak
J. Noailly

doi 10.3389/fbioe.2021.734258

3,096 views
8 citations

REVIEW

Published on 02 Nov 2021

Multiscale Computational Modeling of Vascular Adaptation: A Systems Biology Approach Using Agent-Based Models

Anna Corti
Monika Colombo
Francesco Migliavacca
Jose Felix Rodriguez Matas
Stefano Casarin
Claudio Chiastra

doi 10.3389/fbioe.2021.744560

5,128 views
29 citations

METHODS

Published on 26 Oct 2021

Developing a Lung Model in the Age of COVID-19: A Digital Image Correlation and Inverse Finite Element Analysis Framework

Mohammad Maghsoudi-Ganjeh
Crystal A. Mariano
Samaneh Sattari
Hari Arora
Mona Eskandari

doi 10.3389/fbioe.2021.684778

4,491 views
26 citations

ORIGINAL RESEARCH

Published on 12 Oct 2021

Fiber Rearrangement and Matrix Compression in Soft Tissues: Multiscale Hypoelasticity and Application to Tendon

Claire Morin
Christian Hellmich
Zeineb Nejim
Stéphane Avril

doi 10.3389/fbioe.2021.725047

2,737 views
11 citations

REVIEW

Published on 30 Sep 2021

Towards in silico Models of the Inflammatory Response in Bone Fracture Healing

Laura Lafuente-Gracia
Edoardo Borgiani
Gabriele Nasello
Liesbet Geris

doi 10.3389/fbioe.2021.703725

7,538 views
18 citations

MINI REVIEW

Published on 14 Sep 2021

Porous Geometry Guided Micro-mechanical Environment Within Scaffolds for Cell Mechanobiology Study in Bone Tissue Engineering

Feihu Zhao
Yi Xiong
Keita Ito
Bert van Rietbergen
Sandra Hofmann

doi 10.3389/fbioe.2021.736489

3,879 views
25 citations

ORIGINAL RESEARCH

Published on 27 Aug 2021

A Coupled Mechanobiological Model of Muscle Regeneration In Cerebral Palsy

Stephanie Khuu
Justin W. Fernandez
Geoffrey G. Handsfield

doi 10.3389/fbioe.2021.689714

2,146 views
8 citations

ORIGINAL RESEARCH

Published on 25 Jun 2021

Bone Mechanoregulation Allows Subject-Specific Load Estimation Based on Time-Lapsed Micro-CT and HR-pQCT in Vivo

Matthias Walle
Francisco C. Marques
Nicholas Ohs
Michael Blauth
Ralph Müller
Caitlyn J. Collins

doi 10.3389/fbioe.2021.677985

3,948 views
18 citations

ORIGINAL RESEARCH

Published on 22 Jun 2021

An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

Seyed Ali Elahi
Petri Tanska
Rami K. Korhonen
Rik Lories
Nele Famaey
Ilse Jonkers

doi 10.3389/fbioe.2021.680257

3,703 views
9 citations

ORIGINAL RESEARCH

Published on 18 Jun 2021

Cortical Thickness Adaptive Response to Mechanical Loading Depends on Periosteal Position and Varies Linearly With Loading Magnitude

Corey J. Miller
Silvia Trichilo
Edmund Pickering
Saulo Martelli
Peter Delisser
Lee B. Meakin
Peter Pivonka

doi 10.3389/fbioe.2021.671606

3,115 views
13 citations

ORIGINAL RESEARCH

Published on 14 Jun 2021

Effects of the Haemodynamic Stimulus on the Location of Carotid Plaques Based on a Patient-Specific Mechanobiological Plaque Atheroma Formation Model

Patricia Hernández-López
Myriam Cilla
Miguel Martínez
Estefanía Peña

doi 10.3389/fbioe.2021.690685

1,870 views
10 citations

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Articles

An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation

Evidence-Based Network Modelling to Simulate Nucleus Pulposus Multicellular Activity in Different Nutritional and Pro-Inflammatory Environments

Multiscale Computational Modeling of Vascular Adaptation: A Systems Biology Approach Using Agent-Based Models

Developing a Lung Model in the Age of COVID-19: A Digital Image Correlation and Inverse Finite Element Analysis Framework

Fiber Rearrangement and Matrix Compression in Soft Tissues: Multiscale Hypoelasticity and Application to Tendon

Towards in silico Models of the Inflammatory Response in Bone Fracture Healing

Porous Geometry Guided Micro-mechanical Environment Within Scaffolds for Cell Mechanobiology Study in Bone Tissue Engineering

A Coupled Mechanobiological Model of Muscle Regeneration In Cerebral Palsy

Bone Mechanoregulation Allows Subject-Specific Load Estimation Based on Time-Lapsed Micro-CT and HR-pQCT in Vivo

An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

Cortical Thickness Adaptive Response to Mechanical Loading Depends on Periosteal Position and Varies Linearly With Loading Magnitude

Effects of the Haemodynamic Stimulus on the Location of Carotid Plaques Based on a Patient-Specific Mechanobiological Plaque Atheroma Formation Model

Frontiers in Bioengineering and Biotechnology

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