Cranial Placodes and Neural Crest Interactions in Craniofacial Development

84.5K

views

54

authors

15

articles

Cranial Placodes and Neural Crest Interactions in Craniofacial Development

84.5K

views

54

authors

15

articles

Editorial

22 April 2021

Editorial: Cranial Placodes and Neural Crest Interactions in Craniofacial Development

Jean-Pierre Saint-Jeannet

,

Patrick Blader

and

Lisa A. Taneyhill

3,112 views

2 citations

Editors

3

Jean-Pierre Saint-Jeannet

New York University

University of Maryland, College Park

FR3743 Centre de Biologie Intégrative (CBI)

Impact

About

The vertebrate head is characterized by a complex craniofacial skeleton and paired sensory organs. These structures are derived from two adjacent embryonic cell populations, the neural crest and cranial placodes. The neural crest contributes to the craniofacial skeleton and a subset of cranial ganglia, while cranial placodes form the anterior pituitary, optic lens, inner ear, olfactory epithelium and several cranial ganglia. Defects in cranial neural crest and placode development can cause a wide array of human congenital malformations ranging from craniofacial disorders to hormone imbalance and sensory deficits.

Throughout head development, reciprocal interactions between neural crest and placode cells are essential to drive the coordinated morphogenesis of multiple craniofacial structures. For this Research Topic in Frontiers in Physiology, we welcome contributions that analyze at the cellular, molecular and genetic levels the role of the neural crest and cranial placodes in craniofacial development, and discuss the importance of their interactions for organizing the orofacial complex. Reviews, research articles and opinion pieces are accepted.

The vertebrate head is characterized by a complex craniofacial skeleton and paired sensory organs. These structures are derived from two adjacent embryonic cell populations, the neural crest and cranial placodes. The neural crest contributes to the craniofacial skeleton and a subset of cranial ganglia, while cranial placodes form the anterior pituitary, optic lens, inner ear, olfactory epithelium and several cranial ganglia. Defects in cranial neural crest and placode development can cause a wide array of human congenital malformations ranging from craniofacial disorders to hormone imbalance and sensory deficits.

Throughout head development, reciprocal interactions between neural crest and placode cells are essential to drive the coordinated morphogenesis of multiple craniofacial structures. For this Research Topic in Frontiers in Physiology, we welcome contributions that analyze at the cellular, molecular and genetic levels the role of the neural crest and cranial placodes in craniofacial development, and discuss the importance of their interactions for organizing the orofacial complex. Reviews, research articles and opinion pieces are accepted.

Download ebook

Share

Editors

Jean-Pierre Saint-Jeannet

New York University

University of Maryland, College Park

FR3743 Centre de Biologie Intégrative (CBI)

Impact

84,492 Total views

62,136 Article views

19,824 Article downloads

2,532 Topic views

Published In

Journal Thumbnail

Frontiers in Physiology

Avian Physiology, Craniofacial Biology and Dental Research, Developmental Physiology

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic