CRF and urocortin peptides as modulators of energy balance and behavior during stress

93.3K

views

27

authors

11

articles

CRF and urocortin peptides as modulators of energy balance and behavior during stress

93.3K

views

27

authors

11

articles

Editorial

13 April 2015

Energy metabolism and behavior in the corticotropin-releasing factor family of peptides

James A. Carr

and

David A. Lovejoy

5,172 views

4 citations

Editors

2

Texas Tech University

David A Lovejoy

University of Toronto

Impact

About

Since Hans Selye's seminal work in the 1930's, there have been numerous advances with respect to our understanding of how the nervous and endocrine systems interact to help animals cope with stressors and how chronic stress may adversely impact health. Our modern understanding of stress essentially began in 1954 with the race to discover the hypothalamic releasing factor controlling ACTH secretion and mediating the endocrine response to stressors. Since the isolation of corticotropin releasing factor (CRF) in 1981, interest in CRF has focused not only on its hypophysiotropic function, but also its much broader role in coordinating many of the endocrine, behavioral and autonomic nervous system changes that occur during stress. The goal of this Research Topic is to solicit reviews and general research articles highlighting new research into stress and the hypothalamus-pituitary-adrenal (HPA) axis in the following areas: HPA axis interaction with energy regulating mechanisms during stress; and new studies on the role of CRF and urocortin and urocortins 2 and 3 in behavioral adaptation to stressors.

Since Hans Selye's seminal work in the 1930's, there have been numerous advances with respect to our understanding of how the nervous and endocrine systems interact to help animals cope with stressors and how chronic stress may adversely impact health. Our modern understanding of stress essentially began in 1954 with the race to discover the hypothalamic releasing factor controlling ACTH secretion and mediating the endocrine response to stressors. Since the isolation of corticotropin releasing factor (CRF) in 1981, interest in CRF has focused not only on its hypophysiotropic function, but also its much broader role in coordinating many of the endocrine, behavioral and autonomic nervous system changes that occur during stress. The goal of this Research Topic is to solicit reviews and general research articles highlighting new research into stress and the hypothalamus-pituitary-adrenal (HPA) axis in the following areas: HPA axis interaction with energy regulating mechanisms during stress; and new studies on the role of CRF and urocortin and urocortins 2 and 3 in behavioral adaptation to stressors.

Download ebook

Share

Editors

Texas Tech University

David A Lovejoy

University of Toronto

Impact

93,338 Total views

70,274 Article views

18,691 Article downloads

4,373 Topic views

Published In

Journal Thumbnail

Frontiers in Neuroscience

Neuroendocrine Science

Journal Thumbnail

Frontiers in Endocrinology

Neuroendocrine Science

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic