Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson's Disease

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Editorial

06 April 2021

Editorial: Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson's Disease

Matthew J. Farrer

,

Soraya Bardien

,

Nobutaka Hattori

,

Suzanne Lesage

, 2 more and

Rejko Kruger

2,660 views

9 citations

Editors

5

Soraya Bardien

Stellenbosch University

George Damion Mellick

School of Environment and Science, Griffith Sciences, Griffith University

Institut National de la Santé et de la Recherche Médicale (INSERM)

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The 14th Annual Meeting of the Genetic Epidemiology of Parkinson's Disease (GEoPD) Consortium will be held from the 31st October to 2nd November 2019 in Cape Town, South Africa. To highlight this event we are collaborating with Frontiers in Neurology to put together a Research Topic to reflect state-of-the-art studies on the genetic epidemiology of Parkinson's disease (PD).

PD is a progressive and neurodegenerative disorder with a significant genetic component. Besides rare monogenic forms it is increasingly recognized that even for the common sporadic forms of this disorder, common and rare genetic variants may act in concert with environmental factors, adding substantial complexity to the pathobiology.

The GEoPD consortium was launched in 2005 with the mission to share knowledge, resources and expertise for the common goal; to conduct large-scale collaborative research on the genetics and epidemiology of PD. It is the longest running consortium for advancing the understanding of the pathogenesis of PD and it has developed from the validation of genetic findings to new exploratory projects addressing different populations worldwide. Currently, the GEoPD consortium includes over 60 sites from 30 countries on 6 continents. It is unique in its diversity, both in terms of its member sites and the collection of study participants from diverse ancestral origins. The consortium is open to anyone with a research interest in the genetic and epidemiological aspects of PD.

In this Research Topic, we aim to represent the worldwide diversity of research on PD and welcome the submission of articles from a wide range of geographic regions and on various topics as outlined below:

· Genetic epidemiology studies
· Case-control genetic association studies
· Gene-environment interaction studies
· Candidate gene studies
· Omics approaches
· Animal models
· Disease mechanisms
· Microbiome studies

Original Research, Reviews, Mini-Reviews, Methods, Brief Research Reports and Case Reports would all be acceptable. This is an exciting time in PD research and we hope to capture this excitement and some of the latest research advances in this Research Topic.

We would like to acknowledge Prof Rejko Krueger, from University of Luxembourg, who acted as a coordinator contributing to the preparation of the proposal for this Research Topic as part of the GEoPD.

Frontiers has provided sponsorship for the conference, the 14th Annual Meeting of GEoPD. The resulting Research Topic will be comprised of papers based on the talks given at the conference.

The Topic Editors Owen Ross, Suzanne Lesage, Soraya Bardien, Nobutaka Hattori and George Mellick declare that they are affiliated with the GEoPD consortium on Parkinson's Disease.

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Editors

Soraya Bardien

Stellenbosch University

George Damion Mellick

School of Environment and Science, Griffith Sciences, Griffith University

Institut National de la Santé et de la Recherche Médicale (INSERM)

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Published In

Frontiers in Neurology

Neurogenetics, Neuroepidemiology

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