Although the target of animal virology is manifold, it is clear that many animal virologists now have focused on the precise understanding of the systems biology inherent in virus-host interactions. Since the discovery of viruses, we have experienced numerous “viral/biological phenomena”, and accumulated them in an organized manner into the firm scientific knowledge through systematic extensive and detailed analyses. Biological, molecular biological, and biochemical principles/methods have contributed much to the accomplishment of these investigations. Availability of innovative today’s technology has further encouraged us to elucidate the mysterious interplays between viruses and host cells otherwise impossible before. While these efforts have been proven to be successful, we still need to perform animal model studies to understand the realities of complex and multiple interactions in all natural viral infections. Needless to say, animal models provide important tools for the study of in vivo viral replication and pathogenesis modulated by the host immunity. Pathogenesis questions can not be clarified or are difficult to answer by studies at a molecular/cellular level. In addition, animal experiments can afford us solid scientific bases for exploration of anti-viral drugs and vaccines. It is critically important to have the bottom line evidence that supports the direction of such projects. The increasing need for public health measures is backing up these translational studies.
In this Research Topic entitled “Animal model studies on viral infections”, we accept manuscript submissions on a wide variety of basic and clinical studies as either Review, Mini-review, Perspective, Opinion, Original Research, Methods, or General Commentary article, etc. Many species of animal viruses will be included in this Research Topic. We particularly welcome studies on human viruses or closely related viruses and manuscripts describing viral replication/pathogenesis in vivo and/or anti-virus strategies (drugs and vaccines development).
Although the target of animal virology is manifold, it is clear that many animal virologists now have focused on the precise understanding of the systems biology inherent in virus-host interactions. Since the discovery of viruses, we have experienced numerous “viral/biological phenomena”, and accumulated them in an organized manner into the firm scientific knowledge through systematic extensive and detailed analyses. Biological, molecular biological, and biochemical principles/methods have contributed much to the accomplishment of these investigations. Availability of innovative today’s technology has further encouraged us to elucidate the mysterious interplays between viruses and host cells otherwise impossible before. While these efforts have been proven to be successful, we still need to perform animal model studies to understand the realities of complex and multiple interactions in all natural viral infections. Needless to say, animal models provide important tools for the study of in vivo viral replication and pathogenesis modulated by the host immunity. Pathogenesis questions can not be clarified or are difficult to answer by studies at a molecular/cellular level. In addition, animal experiments can afford us solid scientific bases for exploration of anti-viral drugs and vaccines. It is critically important to have the bottom line evidence that supports the direction of such projects. The increasing need for public health measures is backing up these translational studies.
In this Research Topic entitled “Animal model studies on viral infections”, we accept manuscript submissions on a wide variety of basic and clinical studies as either Review, Mini-review, Perspective, Opinion, Original Research, Methods, or General Commentary article, etc. Many species of animal viruses will be included in this Research Topic. We particularly welcome studies on human viruses or closely related viruses and manuscripts describing viral replication/pathogenesis in vivo and/or anti-virus strategies (drugs and vaccines development).