Bioinformatics Tools (and Web Server) for Cancer Biomarker Development

122.4K

views

132

authors

17

articles

Bioinformatics Tools (and Web Server) for Cancer Biomarker Development

122.4K

views

132

authors

17

articles

Editorial

20 October 2020

Editorial: Bioinformatics Tools (and Web Server) for Cancer Biomarker Development

Longxiang Xie

,

Liuyang Wang

,

Wan Zhu

,

Jing Zhao

and

Xiangqian Guo

4,849 views

3 citations

Editors

5

Henan University

Duke University

Stanford University

Henan University

Chongqing Medical University

Impact

About

Cancer causes more than 9.6 million deaths around the world each year. Despite novel therapeutic methods and improvements in clinical care in recent decades, cancer remains a significant public health burden. One of the difficulties in successful cancer treatment design is the tumor heterogeneity and lack of valid biomarkers to guide the prognosis and therapy.

With the advances in high-throughput (HTP) technologies such as gene microarray and next-generation sequencing, genomic, epigenomic and transcriptomic data of patients are available via public databases such as The Cancer Genome Atlas (TCGA), and Gene Expression Omnibus (GEO). These data sets are great resources that offer additional opportunities in biomarker discovery and validation. Unfortunately, their potential is not fully utilized as and analysis of stored information requires researchers to have a strong background in bioinformatics. Therefore, there is a need for user-friendly online tools and web servers providing such support for investigators involved in oncology biomarker discovery studies.

This Research Topic welcomes manuscripts that develop biomarker related tools, databases and web servers that assist clinical and basic science researchers in biomarker development and validation. Specifically, potential topics should include but are not limited to the following:
(1) Bioinformatics software/algorithms for cancer biomarker screening.
(2) Online tools/web servers for convenient cancer biomarker test and validation.
(3) Databases for collecting and annotating cancer biomarkers.

We welcome Original Research articles, Technology Reports, as well as Review articles.

Cancer causes more than 9.6 million deaths around the world each year. Despite novel therapeutic methods and improvements in clinical care in recent decades, cancer remains a significant public health burden. One of the difficulties in successful cancer treatment design is the tumor heterogeneity and lack of valid biomarkers to guide the prognosis and therapy.

With the advances in high-throughput (HTP) technologies such as gene microarray and next-generation sequencing, genomic, epigenomic and transcriptomic data of patients are available via public databases such as The Cancer Genome Atlas (TCGA), and Gene Expression Omnibus (GEO). These data sets are great resources that offer additional opportunities in biomarker discovery and validation. Unfortunately, their potential is not fully utilized as and analysis of stored information requires researchers to have a strong background in bioinformatics. Therefore, there is a need for user-friendly online tools and web servers providing such support for investigators involved in oncology biomarker discovery studies.

This Research Topic welcomes manuscripts that develop biomarker related tools, databases and web servers that assist clinical and basic science researchers in biomarker development and validation. Specifically, potential topics should include but are not limited to the following:
(1) Bioinformatics software/algorithms for cancer biomarker screening.
(2) Online tools/web servers for convenient cancer biomarker test and validation.
(3) Databases for collecting and annotating cancer biomarkers.

We welcome Original Research articles, Technology Reports, as well as Review articles.

Download ebook

Share

Editors

Henan University

Duke University

Stanford University

Henan University

Chongqing Medical University

Impact

122,376 Total views

81,230 Article views

34,939 Article downloads

6,207 Topic views

Published In

Journal Thumbnail

Frontiers in Oncology

Cancer Genetics

Journal Thumbnail

Frontiers in Genetics

Computational Genomics, Cancer Genetics

Journal Thumbnail

Frontiers in Plant Science

Computational Genomics

Journal Thumbnail

Frontiers in Bioengineering and Biotechnology

Computational Genomics

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic