AUTHOR=Lobachev Oleg , Berthold Moritz , Pfeffer Henriette , Guthe Michael , Steiniger Birte S. 

TITLE=Inspection of Histological 3D Reconstructions in Virtual Reality

JOURNAL=Frontiers in Virtual Reality

VOLUME=2

YEAR=2021

URL=https://www.frontiersin.org/journals/virtual-reality/articles/10.3389/frvir.2021.628449

DOI=10.3389/frvir.2021.628449

ISSN=2673-4192

ABSTRACT=<p>3D reconstruction is a challenging current topic in medical research. We perform 3D reconstructions from serial sections stained by immunohistological methods. This paper presents an immersive visualization solution to quality control (QC), inspect, and analyze such reconstructions. QC is essential to establish correct digital processing methodologies. Visual analytics, such as annotation placement, mesh painting, and classification utility, facilitates medical research insights. We propose a visualization in virtual reality (VR) for these purposes. In this manner, we advance the microanatomical research of human bone marrow and spleen. Both 3D reconstructions and original data are available in VR. Data inspection is streamlined by subtle implementation details and general immersion in VR.</p>