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MINI REVIEW article
Front. Vet. Sci.
Sec. Animal Reproduction - Theriogenology
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1582705
Negative impact of Benign Prostatic Hyperplasia on fertility in dogsa mini-review
Provisionally accepted- 1 University of Warmia and Mazury in Olsztyn, Olsztyn, Poland
- 2 Department of Animal Reproduction with Clinic, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland, Olsztyn, Poland
The aim of this article is to provide a comprehensive review of the negative impact of benign prostatic hyperplasia (BPH) on fertility in dogs. BPH is the most common disease of the prostate gland and one of the major causes of infertility in dogs, associated with impaired semen quality.Hormonal imbalance, oxidative stress, biochemical changes in prostatic fluid and haematospermia have been discussed as causes of reduced semen quality in dogs with BPH.Chronic prostatitis often occurs concurrently with BPH and has an additive negative effect on semen quality and fertility. In breeding dogs with infertility associated with BPH, treatment with the anti-androgen osaterone acetate or the 5α-reductase inhibitor finasteride is recommended to reduce prostate size and clinical symptoms and to restore fertility. Combined occurrence of BPH and chronic prostatitis requires simultaneous treatment of both conditions, including microbials with good penetration into the prostate. The use of antioxidants in the supportive treatment of BPH seems reasonable.
Keywords: dog, Benign prostatic hyperplasia, Fertility, Semen quality, Prostate
Received: 24 Feb 2025; Accepted: 31 Mar 2025.
Copyright: © 2025 Domosławska-Wyderska, Zduńczyk and Rafalska. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Anna Domosławska-Wyderska, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland
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