94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
REVIEW article
Front. Vet. Sci.
Sec. Animal Nutrition and Metabolism
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1565501
The biological functions of proanthocyanidin and its application in pig production
Provisionally accepted- Guangdong Academy of Agricultural Sciences (GDAAS), Guangzhou, China
Proanthocyanidins (PACs) are natural polyphenolic compounds widely distributed in various pl ants, which are mixtures of oligomers and polymers formed by the polymerization of different numbers of catechins and epicatechins. PACs exhibit a range of biological activities, includin g antioxidant, anti-inflammatory, anti-cancer, anti-atherosclerotic, hypoglycemic, and antihyperte nsive effects, as well as the ability to regulate intestinal flora and promote fat metabolism. T hese properties render PACs highly promising for applications in the food, pharmaceutical, an d cosmetic industries, garnering substantial interest from researchers globally. Additionally, PA Cs demonstrate significant nutritional benefits in animal husbandry. Dietary PACs can enhance animal growth, mitigate oxidative stress, decrease feeding expenses, and offer an environment ally friendly, antibiotic-free alternative. Therefore, PACs have great application potential in the field of pig production. This article reviews the basic properties, biological functions, and res earch status and application in pig production of PACs, aiming to provide theoretical guidance for the development of substitute antibiotic feed additives.
Keywords: Proanthocyanidins, biological functions, antioxidant, anti-inflammatory, pigs
Received: 23 Jan 2025; Accepted: 28 Feb 2025.
Copyright: © 2025 Yu, Sun, Chen, Wang, Li, Wang, Wang and Lin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zhenjiang Wang, Guangdong Academy of Agricultural Sciences (GDAAS), Guangzhou, China
Sen Lin, Guangdong Academy of Agricultural Sciences (GDAAS), Guangzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.