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CASE REPORT article
Front. Vet. Sci.
Sec. Veterinary Emergency and Critical Care Medicine
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1553617
This article is part of the Research Topic Case Reports in Veterinary Neurology and Neurosurgery View all 14 articles
Presumed Cerebral Salt Wasting Syndrome in a 10-week-old
Provisionally accepted- College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States
This case report describes a rare presentation of cerebral salt-wasting syndrome (CSW) in a 10-week-old German Shorthaired Pointer following a traumatic brain injury. The patient presented stuporous and tetraplegic with advanced imaging revealing a depressed skull fracture and active brain hemorrhage. Following surgical intervention, the dog exhibited persistent hypovolemia and hyponatremia prompting treatment with intravenous hypertonic saline and enteral sodium supplementation. Positive response to sodium supplementation, coupled with elevated fractional excretion of uric acid (FEUA) despite clinical improvement, supported the diagnosis of CSW. This report contributes novel insights into CSW in veterinary medicine, emphasizing the distinctive features of its presentation, diagnostic considerations, and treatment responses. The clinical utility of FEUA as a diagnostic tool is highlighted for the first time in a canine patient, providing a valuable tool for differentiation. This information enhances veterinary practitioners' awareness, facilitating more accurate diagnoses and tailored treatment strategies for similar cases in the future.
Keywords: canine, skull fracture, Hyponatremia, Traumatic Brain Injury, Hypovolemia
Received: 31 Dec 2024; Accepted: 11 Mar 2025.
Copyright: © 2025 Jackson, Fefer, Hansen and Munana. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Elizabeth Jackson, College of Veterinary Medicine, North Carolina State University, Raleigh, 27607, North Carolina, United States
Karen R. Munana, College of Veterinary Medicine, North Carolina State University, Raleigh, 27607, North Carolina, United States
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