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ORIGINAL RESEARCH article

Front. Vet. Sci.

Sec. Veterinary Infectious Diseases

Volume 12 - 2025 | doi: 10.3389/fvets.2025.1552115

This article is part of the Research Topic High-Impact Respiratory RNA Virus Diseases, Volume II View all articles

Genetic Characterization of an H3N2 Canine Influenza Virus Strain in China in 2023—Acquisition of Novel Human-Like Amino Acid Substitutions

Provisionally accepted
Sihan Li Sihan Li Liangyu Chu Liangyu Chu Yancheng Zhang Yancheng Zhang Yaxuan Yu Yaxuan Yu Guiqing Wang Guiqing Wang *
  • Northeastern University, Shenyang, Liaoning Province, China

The final, formatted version of the article will be published soon.

    We sincerely appreciate the constructive feedback and valuable suggestions provided by the editor and reviewer, which have significantly enhanced the quality of our manuscript. Your insights have been instrumental in guiding our future research directions.Reviewer 1 commented: This paper presents an intriguing study of the canine H3N2 virus by conducting a comparative analysis of the possible origins of the corresponding segments of this particular genome.I have some observations:Be aware of the abbreviation for influenza A virus and avian influenza virus, as it can be confusing; I suggest reviewing this abbreviation.Response: Thank you for your valuable suggestion. To avoid confusion, we have revised the abbreviation for "influenza A virus" to IAV and "avian influenza virus" to AvIV in the manuscript.Change "mixing vessel" to "intermediate species."Response: Thank you for your suggestion. We have revised "mixing vessel" to "intermediate species" as recommended by the reviewer.

    Keywords: H3N2 canine influenza virus, dog, HA1 202I, M1 227T, PB2 107N

    Received: 27 Dec 2024; Accepted: 18 Feb 2025.

    Copyright: © 2025 Li, Chu, Zhang, Yu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Guiqing Wang, Northeastern University, Shenyang, 110819, Liaoning Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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