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ORIGINAL RESEARCH article

Front. Vet. Sci.
Sec. Veterinary Infectious Diseases
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1512387
This article is part of the Research Topic Biosecurity of Infectious Diseases in Veterinary Medicine View all articles

Evaluation of the viricidal effects of UV254 light on common airborne porcine viruses

Provisionally accepted
YingWu Qiu YingWu Qiu 1Qunhui Li Qunhui Li 2Wenkai Zhao Wenkai Zhao 2昊 常 昊 常 1Junhua Wang Junhua Wang 3Gao Qi Gao Qi 1Qingfeng Zhou Qingfeng Zhou 1Guihong Zhang Guihong Zhang 1Lianxiang Wang Lianxiang Wang 2Lang Gong Lang Gong 4*
  • 1 South China Agricultural University, Guangzhou, Guangdong Province, China
  • 2 Guangdong Enterprise Key Laboratory for Animal Health and Environmental Control, Guangzhou, Guangdong, China
  • 3 Foshan Comwin Light & Electricity Co., Ltd., Gaomin District, Foshan, China
  • 4 College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

The final, formatted version of the article will be published soon.

    UV exposure is a common method of disinfection and sterilization. In the present study, the parallel beam test was performed to collect fluids containing infectious viruses using a parallel beam apparatus after UV254 irradiation (0, 0.5, 1, 3, 5, 7, 10, or 20 mJ/cm 2 ). The air sterilization test was performed by irradiating the air in the ducts with UV254 light (0, 1, 2, 3, 4, or 6 mJ/cm 2 ) to collect airborne particles containing viruses through the air sterilization equipment. Furthermore, viral inactivation was assessed based on cytopathic effect (CPE) detection and immunofluorescent assays (IFA). Both the CPE and immunofluorescence signal intensity decreased as the UV254 dose increased.The UV254 doses required to inactivate ASFV (10 7.75 copies/mL), PRRSV (10 6.29 copies/mL), and PEDV (10 7.71 copies/mL) in the water were 3, 1, and 1 mJ/cm 2 , respectively. The UV254 dose required to inactivate ASFV (10 4.06 copies/mL), PRRSV (10 3.06 copies/mL), and PEDV (10 4.68 copies/mL) in the air was 1 mJ/cm 2 . This study provides data required for biosecurity prevention and control in swine farms.

    Keywords: UV radiation, Air disinfection, ASFV, PRRSV, PEDV

    Received: 16 Oct 2024; Accepted: 09 Jan 2025.

    Copyright: © 2025 Qiu, Li, Zhao, 常, Wang, Qi, Zhou, Zhang, Wang and Gong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Lang Gong, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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