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ORIGINAL RESEARCH article

Front. Vet. Sci.
Sec. Animal Nutrition and Metabolism
Volume 12 - 2025 | doi: 10.3389/fvets.2025.1501117

Influence of Fermented Milk Permeate Containing Antimicrobial Lactobacillus and Galactooligosaccharides on Growth Performance and Health Parameters in Neonatal Piglets

Provisionally accepted
Sarunas Badaras Sarunas Badaras Vytaute Starkute Vytaute Starkute Ernestas Mockus Ernestas Mockus Modestas Ruzauskas Modestas Ruzauskas Dovile Klupsaite Dovile Klupsaite Erika Mozuriene Erika Mozuriene Jurgita Dailidaviciene Jurgita Dailidaviciene Agila Dauksiene Agila Dauksiene Laurynas Vadopalas Laurynas Vadopalas Elena Bartkiene Elena Bartkiene *
  • Lithuanian University of Health Sciences, Kaunas, Lithuania

The final, formatted version of the article will be published soon.

    The study aimed to compare the effects of fermented milk permeate (MP) with Pediococcus pentosaceus (MPPp) and P. acidilactici (MPPa) on growth and blood plasma parameters, faecal microbial, metataxanomic, and physicochemical characteristics in Topigs Norsvin Yorkshire piglets. Thirty-six 1-day-old piglets were divided into three groups: (i) control group (C), (ii) MP-Pp group, and (iii) MPPa group. The treated groups, additionally to full-fledged combined pre starter, received 25 mL of MP daily. After the experiment, MPPa piglets showed the highest weight gain, while MPPp piglets had the highest IgM concentration. Both experimental groups had higher Lactobacillus counts in faeces. Although, Lactobacillus and Enterobacteria numbers increased, they were not directly related to growth performance. MPPa piglets faeces had a unique volatile compound profile, including higher butanoic acid and indole levels, which may be linked to differences in their faeces metataxanomic profile. The MPPp group had more different bacterial variety pattern in comparing with the control and MPPa groups.There were different amounts of separate bacterial species in faeces of piglets after the experiment, but the MPPa group, contained highest amount of Parabacteroides sp. 12306, Terrisporobacter sp. 34393, Holdemanella sp. 36738 and Lachnospiraceae sp. In conclusion, feeding piglets with MPPa would be beneficial for better weight gain, while this dietary inclusion also gives a proliferation of certain bacteria species and a unique VC profile in faeces. This study highlights the need for deeper research into the metabolic pathways behind these findings.

    Keywords: metataxanomic, by-products bioconversion, Immunoglobulins, volatile compounds, antimicrobials

    Received: 24 Sep 2024; Accepted: 20 Jan 2025.

    Copyright: © 2025 Badaras, Starkute, Mockus, Ruzauskas, Klupsaite, Mozuriene, Dailidaviciene, Dauksiene, Vadopalas and Bartkiene. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Elena Bartkiene, Lithuanian University of Health Sciences, Kaunas, Lithuania

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.