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REVIEW article
Front. Vet. Sci.
Sec. Veterinary Infectious Diseases
Volume 12 - 2025 |
doi: 10.3389/fvets.2025.1492144
Research progress on Haemophilus parasuis vaccines
Provisionally accepted- College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China
Haemophilus parasuis (HPS) is the causative agent of porcine Glässer's disease, which has become prevalent in China in recent years. It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other upper respiratory tract pathogens, causing heavy economic losses to the pig industry. Vaccination is an important means to prevent and control HPS infection, and the currently available vaccines are mainly the inactivated type or subunit vaccines containing immunogenic HPS proteins. This study reviews recent advances in HPS vaccines, analyzes the relative effectiveness of the components of subunit vaccines and discusses the advantages and disadvantages of each vaccine type.The goal is to provide insights for the development of more effective vaccines against Haemophilus parasuis infections in pigs.
Keywords: Haemophilus parasuis, Glässer's disease, Vaccines, Pathogenesis, Glaesserella parasuis
Received: 06 Sep 2024; Accepted: 22 Jan 2025.
Copyright: © 2025 Duan, Hao, Feng, Shu and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
yue Hao, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China
Jianhong Shu, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China
Yulong He, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China
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