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CASE REPORT article

Front. Vet. Sci.
Sec. Veterinary Neurology and Neurosurgery
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1522745
This article is part of the Research Topic Case Reports in Veterinary Neurology and Neurosurgery View all 11 articles

Case Report: FGF4L1 Retrogene Insertion is Lacking in the Tall Dachshund Phenotype

Provisionally accepted
Stacey Sullivan Stacey Sullivan 1*Katarzyna Julia Szeremeta Katarzyna Julia Szeremeta 2Michelle Anne Kutzler Michelle Anne Kutzler 3
  • 1 College of Veterinary Medicine, Auburn University, Auburn, United States
  • 2 The International Working Teckel, Mannheim, Germany
  • 3 College of Agricultural Sciences, Oregon State University, Corvallis, Oregon, United States

The final, formatted version of the article will be published soon.

    Two retrogene insertions, FGF4L1 (formerly 18-FGF4, colloquially CDPA) and FGF4L2 (formerly 12-FGF4, colloquially CDDY), have recently been discovered as determinants of short leg phenotype in dogs. This case study is comprised of a family of standard wirehaired dachshunds in which the dogs lacking the FGF4L1 gene exhibit a tall phenotype. The tall phenotype in the dachshunds of this report precludes the dog's working function of den work.The data presented in this report provide information as to how FGF4L1 status could be used in making breeding decisions in dachshunds to maintain working ability without compromising animal health.

    Keywords: case report, CDDY, CDPA, Chondrodystrophy, Chondrodysplasia, FGF4L1, FGF4L2, Limb-length

    Received: 04 Nov 2024; Accepted: 11 Dec 2024.

    Copyright: © 2024 Sullivan, Szeremeta and Kutzler. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Stacey Sullivan, College of Veterinary Medicine, Auburn University, Auburn, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.