Youn-woo Choo ¹ Jun-Sik Cho ¹ Ah-Young Cha ² Hwi-Yool Kim ¹ Jung-Moon Kim ^1,2*

• ¹ Konkuk University, Seoul, Republic of Korea
• ² sky animal medical center, Yongin, Republic of Korea

Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA), also called Herlyn-Werner-Wunderlich syndrome is an extremely rare Mullerian duct anomaly accompanied by Wolffian duct anomalies. A 10-year-old intact male Yorkshire Terrier weighing 3.35kg was presented with anorexia, depression, vomiting and abdominal pain. Through Radiography, Ultrasonography and Computed Tomography, uterine didelphys, obstructed hemivagina, a cystic structure around right uterus, and right renal agenesis were revealed, which led to the diagnosis of OHVIRA syndrome. An ovariohysterectomy and decompression of the obstructed right hemivagina were performed, and the cystic structure near the right uterine horn was removed by en bloc resection, along with the right uterus and ovary. After the surgical intervention, the patient's symptoms including abdominal pain, anorexia, and depression were immediately resolved. The patient was followed up for one month postoperatively with ultrasonography at two-week intervals, which revealed the progression of mild fluid retention in the right hemivagina. However, no additional urogenital findings were identified, and the patient continues to display no overt clinical symptoms. This case report details the diagnosis and surgical treatment of the first documented case of OHVIRA syndrome in an animal. Unlike in human medicine, where vaginal septectomy is performed to prevent dilatation of the obstructed hemivagina and thereby resolve clinical symptoms, performing ovariohysterectomy combined with fluid aspiration from the obstructed hemivagina showed a favorable postoperative prognosis in the dog.