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CASE REPORT article

Front. Vet. Sci.
Sec. Veterinary Experimental and Diagnostic Pathology
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1467448
This article is part of the Research Topic Innovative Approaches in Veterinary Pathology: Diagnostics, Therapeutics, and Zoonotic Threats View all articles

Diffuse large B-cell lymphoma presenting as congestive heart failure in a cat

Provisionally accepted
Jake Johnson Jake Johnson Hannah Melhorn Hannah Melhorn Sonya Karchemskiy Sonya Karchemskiy Emily Karlin Emily Karlin Perry Bain Perry Bain John Rush John Rush Cornelia Peterson Cornelia Peterson *
  • Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, United States

The final, formatted version of the article will be published soon.

    Cardiac lymphoma is uncommon in cats and is rarely considered as a differential diagnosis for congestive heart failure. A 10-year-old neutered male domestic short-haired cat with clinical histories of feline immunodeficiency virus, diabetes mellitus, and congestive heart failure was humanely euthanized. Post-mortem evaluation demonstrated a massively infiltrative round cell neoplasm of the heart, resulting in CHF. Immunohistochemistry of neoplastic tissue was consistent with diffuse large B-cell lymphoma. This case demonstrates a peculiar presentation of cardiac diffuse large B-cell lymphoma, with chronic feline lentiviral infection possibly contributing to disease initiation and progression.

    Keywords: feline, Cardiac neoplasia, Diffuse large B-cell lymphoma, Immunohistochemistry, Feline immunodeficiency virus

    Received: 19 Jul 2024; Accepted: 09 Sep 2024.

    Copyright: © 2024 Johnson, Melhorn, Karchemskiy, Karlin, Bain, Rush and Peterson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Cornelia Peterson, Cummings School of Veterinary Medicine, Tufts University, North Grafton, 01536, Massachusetts, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.