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ORIGINAL RESEARCH article

Front. Vet. Sci.
Sec. Veterinary Imaging
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1462437
This article is part of the Research Topic Outstanding Advances in Veterinary Diagnostic Ultrasonography: Novel Milestones in Disease Detection, Prediction, and Treatment View all 4 articles

Assessment of myocardial function in Retrievers with dilated cardiomyopathy using 2D speckle tracking echocardiography: A pilot study

Provisionally accepted
Lina Hamabe Lina Hamabe 1Kazumi Shimada Kazumi Shimada 1Miki Hirose Miki Hirose 1Mizuki Hasegawa Mizuki Hasegawa 1Aki Takeuchi Aki Takeuchi 1Tomohiko Yoshida Tomohiko Yoshida 2Daigo Azakami Daigo Azakami 1Ahmed S. Mandour Ahmed S. Mandour 1,3Ryou Tanaka Ryou Tanaka 1*
  • 1 Tokyo University of Agriculture and Technology, Fuchu, Japan
  • 2 Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
  • 3 Suez Canal University, Ismaïlia, Ismailia, Egypt

The final, formatted version of the article will be published soon.

    Early diagnosis of canine dilated cardiomyopathy (DCM) is complicated by the presence of a prolonged asymptomatic phase, for which a comprehensive evaluation of myocardial function is essential. This pilot study was conducted to evaluate the myocardial function in dogs with DCM using two-dimensional speckle tracking echocardiography (2D-STE). Nine client-owned Retrievers with DCM and twelve client-owned clinically normal Retrievers were comparatively evaluated using standard echocardiography and 2D-STE. Dogs with DCM were characterized by significant dilation of the left ventricle (LV), thinning of the LV wall, and myocardial hypokinesis when compared to clinically normal dogs. The global strain analysis showed a significant reduction of strain in both radial and circumferential directions, and the regional strain analysis revealed a greater degree of myocardial dysfunction at the LV free wall in the circumferential direction in dogs with DCM. The regional strain analysis also demonstrated a difference in the pattern of contraction between dogs with DCM and clinically normal dogs. The results of this study illustrate the ability of 2D-STE to evaluate both global and regional myocardial function in dogs with DCM and show differences between dogs with DCM and clinically normal dogs.

    Keywords: 2D-STE, canine dilated cardiomyopathy, dog, Echocardiography, Retrievers, Strain analysis

    Received: 10 Jul 2024; Accepted: 15 Oct 2024.

    Copyright: © 2024 Hamabe, Shimada, Hirose, Hasegawa, Takeuchi, Yoshida, Azakami, Mandour and Tanaka. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ryou Tanaka, Tokyo University of Agriculture and Technology, Fuchu, Japan

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