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ORIGINAL RESEARCH article

Front. Vet. Sci.
Sec. Comparative and Clinical Medicine
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1446770

Effect of Wei Qi Booster on Immune and Anti-oxidative Function in Aged Mice

Provisionally accepted
Ma Shuang Ma Shuang 1Yuming Chen Yuming Chen 1Zhilong Zhou Zhilong Zhou 1Aituan Ma Aituan Ma 2*
  • 1 Hebei University of Engineering, Handan, China
  • 2 Hebei Agricultural University, Baoding, Hebei, China

The final, formatted version of the article will be published soon.

    This research was conducted to examine the impact of Wei Qi Booster (WQB) on immune parameters and anti-oxidative function in aged mice. Fifty aged mice were randomly assigned to five different groups. Group A was designated as the control group. Mice in Group B were receiving Levamisole at 10 mg/kg body weight. Each mouse in groups C, D and E received 0.1%, 1%, and 2% WQB, respectively. Another ten young mice, designated as group F, were fed regularly. The mice were fed according to the above methods for 28 days. Results showed that relative to the control group, the body weight and immune organs indexes experienced a substantial rise in the group with 1% WQB. In addition, 1% WQB could improve the activity of SOD and reduce the MDA levels. Expressions of CD4 and sIgA increased while CD8 decreased in the jejunum of aged mice treated with WQB. IL2 and IFN-γ levels increased in the 1% WQB group, showing no notable difference compared to the young mice group. The results demonstrated that WQB can elevate immune levels and enhance anti-oxidative functions in aged mice.

    Keywords: Traditional Chinese veterinary medicine (TCVM), Wei Qi Booster (WQB), Aged mice, immune, anti-oxidative

    Received: 10 Jun 2024; Accepted: 15 Jul 2024.

    Copyright: © 2024 Shuang, Chen, Zhou and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Aituan Ma, Hebei Agricultural University, Baoding, 071001, Hebei, China

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