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ORIGINAL RESEARCH article
Front. Vet. Sci.
Sec. Veterinary Infectious Diseases
Volume 11 - 2024 |
doi: 10.3389/fvets.2024.1418553
This article is part of the Research Topic Wildlife-Domestic Animal Interface: Threat or Sentinel? View all 6 articles
The First Outbreak of Feline Panleukopenia Virus Infection in Captive Pallas's Cats in Xining Wildlife Park
Provisionally accepted
Jingjie Wei
1,2
Yuqi Shi
2
Xiaofei Wang
3*
Shunfu He
3*
Xinzhang Qi
3*
Rong Lu
3*
Yuhang Gao
2*
Zichen Liu
2
Yingyun Wang
2
Yuanheng Wu
2*
Yipeng Jin
2*- 1 China Agricultural University, Beijing, China
- 2 Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing, Beijing Municipality, China
- 3 Other, Xining, Qinghai, China
A significant aspect of this study's novelty lies in the detailed molecular characterization of the FPV strain isolated from Pallas's cats. Specifically, the identification of a novel synonymous mutation in the VP2 gene enhances our understanding of FPV's genetic diversity. Although this mutation does not alter the amino acid sequence, it may have implications for the virus's evolution and adaptability, potentially affecting how the virus interacts with the host immune system or responds to environmental pressures. Phylogenetic analysis confirmed the close relationship of this isolate with other prevalent FPV strains in China, suggesting a possible common origin or recent transmission events. These findings indicate that FPV strains circulating in different feline populations may share a genetic lineage, underscoring the importance of monitoring genetic variations to track the virus's spread and evolution. These molecular insights are crucial for understanding FPV's epidemiology and developing targeted interventions. By identifying specific genetic markers, we can improve diagnostic tools, enhance vaccine design, and implement more effective biosecurity measures. The study highlights the need for ongoing surveillance and genetic analysis of FPV in both wild and domestic feline populations to prevent future outbreaks and protect endangered species like the Pallas's cat.
Keywords: Feline panleukopenia virus, Pallas's Cats, Virus isolation and identification, pathogenicity, Virus detection
Received: 16 Apr 2024; Accepted: 08 Aug 2024.
Copyright: © 2024 Wei, Shi, Wang, He, Qi, Lu, Gao, Liu, Wang, Wu and Jin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaofei Wang, Other, Xining, Qinghai, China
Shunfu He, Other, Xining, Qinghai, China
Xinzhang Qi, Other, Xining, Qinghai, China
Rong Lu, Other, Xining, Qinghai, China
Yuhang Gao, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing, 100083, Beijing Municipality, China
Yuanheng Wu, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing, 100083, Beijing Municipality, China
Yipeng Jin, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing, 100083, Beijing Municipality, China
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