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CASE REPORT article

Front. Vet. Sci.
Sec. Veterinary Emergency and Critical Care Medicine
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1418194

Secondary systemic candidiasis in dog Case report: A rare secondary systemic candidiasis as a bite wound complication in a dog

Provisionally accepted
  • Department of Veterinary Emergency and Critical Care, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea

The final, formatted version of the article will be published soon.

    An 11-year-old, 4.8 kg, intact male mixed-breed dog was evaluated for a bite wound that had occurred a day prior to consultation. On examination, the patient exhibited signs of early to-late decompensatory shock, hemothorax, pneumothorax, and rib fractures. Initial shock management and resuscitation were performed. After several days of stabilization, exploratory thoracotomy, thoracic wall reconstruction, culture sampling, and antibiotic susceptibility tests were conducted. Empirical antimicrobial treatments were performed while pending culture results. Despite aggressive antimicrobial therapy, the patient had focal seizures and wound dehiscence, presumably due to the worsening of infection and inflammation. Necrotic tissues adjacent to the dehiscence were debrided, and the wound was opened. A previous analysis of wound and blood cultures identified Candida glabrata, and itraconazole was initiated in accordance with the culture results. Successful treatment was achieved, and the wound was closed. The patient remained healthy after 2 months of monitoring. To the best of our knowledge, this was the first case report of systemic candidiasis in a dog secondary to a bite wound diagnosed via blood culture. Additionally, this case highlights successful treatment with itraconazole. 1 삭제함: C. glabrata, which was detected in the current patient, is 226 distinguished from other Candida species (C. albicans, C. tropicalis, 227 and C. guilliermondii) that belong to the CTG clade. These species 228 convert CUG codons to serine rather than leucine (26).

    Keywords: antifungal agent, Itraconazole, Bite wound, Candida, Systemic Candidiasis

    Received: 16 Apr 2024; Accepted: 26 Sep 2024.

    Copyright: © 2024 Geum and Han. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Hyun-Jung Han, Department of Veterinary Emergency and Critical Care, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea

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