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ORIGINAL RESEARCH article

Front. Vet. Sci.
Sec. Comparative and Clinical Medicine
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1395360

Measuring the effect of the anti-Nerve Growth Factor (NGF) antibodies bedinvetmab and frunevetmab on Quality of Life in dogs and cats with osteoarthritis using a validated healthrelated quality of life outcome measure: An observational real-world study

Provisionally accepted
Jacqueline Reid Jacqueline Reid 1*Edwina Gildea Edwina Gildea 2Vinny Davies Vinny Davies 1Jill Thompson Jill Thompson 2Marian Scott Marian Scott 1
  • 1 University of Glasgow, Glasgow, United Kingdom
  • 2 Zoetis (Ireland), Dublin, Ireland

The final, formatted version of the article will be published soon.

    Dogs and cats are naturally occurring models of osteoarthritis (OA) in humans. This paper describes a real world study, using a validated health-related quality of life (HRQL) structured questionnaire instrument completed by the owner, which demonstrates the improvement in HRQL in osteoarthritic dogs and cats following treatment with the licensed anti -NGF mAbs bedinvetmab and frunevetmab respectively. Although anti-NGF mAbs have been developed for use in people, they have not yet received market authorisation and this translational study contributes to the body of evidence supporting their use in OA.

    Keywords: Edwina Gildea: Conceptualization, Data curation, methodology, project administration, supervision, Writing -review & editing Methodology, Writing -original draft, Writing -review & editing. Jill Thompson: Project administration

    Received: 03 Mar 2024; Accepted: 20 Jun 2024.

    Copyright: © 2024 Reid, Gildea, Davies, Thompson and Scott. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jacqueline Reid, University of Glasgow, Glasgow, United Kingdom

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.