Skip to main content

ORIGINAL RESEARCH article

Front. Vet. Sci.
Sec. Veterinary Infectious Diseases
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1245569
This article is part of the Research Topic Antiviral Natural Products and Vaccines for Porcine Viruses View all articles

Antiviral Activity of SAFER ® , a Commercial Acidifying Desiccant Powder, Against African Swine Fever Virus (ASFV)

Provisionally accepted
Bich Ngoc T. Trinh Bich Ngoc T. Trinh 1Elodie Lazenec Elodie Lazenec 2Lai T. Ngoc Ha Lai T. Ngoc Ha 1Maria Matard-Mann Maria Matard-Mann 2Luong Tan Phat Luong Tan Phat 2Anne Morvan Anne Morvan 2Anne-Cecile Delahaye Anne-Cecile Delahaye 2Pi Nyvall Collén Pi Nyvall Collén 2Le Van Phan Le Van Phan 1*
  • 1 Vietnam National University of Agriculture, Hanoi, Vietnam
  • 2 Olmix SA, Bréhan, France

The final, formatted version of the article will be published soon.

    African swine fever (ASF) is one of the most deadly swine diseases, causing significant economic losses, threatening food security, and limiting pig production in affected countries. In the absence of an effective ASF vaccine, prevention and control of ASF depend mainly on effective biosecurity measures. In this study, the efficacy of SAFER ® , a powdered disinfectant containing clay, an acid complex, and the active ingredient thyme essential oil, was tested against the ASF virus. The results showed that ASFV isolate (VNUA/HY/ASF1/Vietnam/2019) was inactivated by 3.5 and 5Log 10 HAD 50 /ml after 20 and 120 minutes of treatment with SAFER ® , 2 respectively. When body fluids contaminated with ASFV, such as blood, saliva, urine, and feces, were treated with SAFER ® for 20 minutes, the ASFV titer was reduced by 1.6, 2.2, 2.0, and 2.2 Log 10 HAD 50 /ml, respectively.

    Keywords: ASFV, Antiviral activity, Body Fluids, SAFER ®, African Swine Fever

    Received: 23 Jun 2023; Accepted: 19 Jul 2024.

    Copyright: © 2024 Trinh, Lazenec, Ngoc Ha, Matard-Mann, Tan Phat, Morvan, Delahaye, Nyvall Collén and Van Phan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Le Van Phan, Vietnam National University of Agriculture, Hanoi, Vietnam

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.