AUTHOR=Tremolada Giovanni , Griffin Lynn , Manchester Alison C. , Aboellail Tawfik , Lapsley Janis M. , Selmic Laura E. TITLE=Primary extraskeletal osteosarcoma of the post-hepatic caudal vena cava in a dog—Case report JOURNAL=Frontiers in Veterinary Science VOLUME=10 YEAR=2023 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2023.1197236 DOI=10.3389/fvets.2023.1197236 ISSN=2297-1769 ABSTRACT=

Extraskeletal osteosarcoma (EOSA) in dogs is a rare malignant mesenchymal tumor of somatic soft tissues or more commonly visceral organs with a poor prognosis. In dogs, EOSAs have been described as arising from multiple locations, but differently from humans, never from a main vessel. In this report, we describe the first case of an EOSA arising from the post-hepatic caudal vena cava in a 7-year-old male neutered mix breed dog. This report focuses on the description of the diagnostic challenges to obtain a preoperative diagnosis, highlights the importance of histopathology for a correct diagnosis, and introduces a new differential diagnosis for an animal presenting with a suspected thrombus of the vena cava.