AUTHOR=Genova Jansller Luiz , Rupolo Paulo Evaristo , Azevedo Liliana Bury de , Henz Daniela , Carvalho Silvana Teixeira , Kipper Marcos , Gonçalves Giovana de Arruda Castelo , Vilela Hellen Lazarino Oliveira , Pasquetti Tiago Junior , Oliveira Newton Tavares Escocard de , Dietrich Andrei Roberto Manelli , Carvalho Paulo Levi de Oliveira 

TITLE=β-mannanase supplementation in diets reduced in 85 kcal metabolizable energy/kg containing xylanase-phytase improves gain to feed ratio, nutrient usage, and backfat thickness in finisher pigs

JOURNAL=Frontiers in Veterinary Science

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2023.1144692

DOI=10.3389/fvets.2023.1144692

ISSN=2297-1769

ABSTRACT=<p>This study aimed to assess the effects of β-mannanase supplementation in metabolizable energy (ME)-reduced diets containing xylanase-phytase on performance, fecal score, blood biochemical and immunological profile, apparent total tract digestibility (ATTD), digesta passage rate, fecal microbiome, carcass traits and meat quality in finisher pigs (<italic>n</italic> = 40 entire male hybrid, 26.0 ± 0.9 kg) randomly assigned to 1 of 4 dietary treatments: a control diet containing isolated phytase and xylanase valued at 40 kcal of ME/kg (CD0), CD0 + β-mannanase (0.3 g/kg valued at 30 kcal of ME/kg) (CD70), CD0 + β-mannanase (0.3 g/kg valued at 45 kcal of ME/kg) (CD85), and CD0 + β-mannanase (0.3 g/kg valued at 60 kcal of ME/kg) (CD100), with 10 pen replicates. Pigs fed CD0 diet showed (<italic>P</italic> = 0.002) greater ADFI. However, pigs fed CD0 diet showed (<italic>P</italic> = 0.009) lower G:F than those provided CD70 or CD85 diets. A greater (<italic>P</italic> &lt; 0.001) superoxide dismutase concentration was observed in pigs fed CD70 diet. Pigs fed CD85 diet showed (<italic>P</italic> = 0.002) greater digestible protein than pigs fed CD0 or CD100 diets. Pigs fed CD70 diet showed an increase of 11.3% in digestible protein than those fed CD0 diet. In addition, greater (<italic>P</italic> &lt; 0.001) digestible energy was observed in pigs fed CD85 diet. Pigs fed CD0 or CD100 diets showed greater (<italic>P</italic> &lt; 0.05) Firmicutes:Bacteroidota ratio than those fed CD85 diet. The Muribaculaceae was more abundant (<italic>P</italic> = 0.030) in pigs fed CD70 diet than in those fed CD0 diet. The <italic>Prevotella</italic> was more abundant (<italic>P</italic> = 0.045) in pigs fed CD85 diet than in those fed CD100 diet. In conclusion, β-mannanase supplementation in diets containing xylanase-phytase allows reducing 85 kcal of ME/kg because it improves gain to feed ratio, energy and protein usage, and backfat thickness without metabolic and intestinal ecosystem disorders in finisher pigs.</p>