AUTHOR=Nelsen April , Lager Kelly M. , Stasko Judith , Nelson Eric , Lin Chun-Ming , Hause Ben M. TITLE=Identification of Pulmonary Infections With Porcine Rotavirus A in Pigs With Respiratory Disease JOURNAL=Frontiers in Veterinary Science VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.918736 DOI=10.3389/fvets.2022.918736 ISSN=2297-1769 ABSTRACT=
While rotavirus (RV) is primarily known to cause gastroenteritis in many animals, several epidemiological studies have shown concurrent respiratory symptoms with fecal and nasal virus shedding. However, respiratory RV infections have rarely been investigated. By screening clinical samples submitted for diagnostic testing, porcine rotavirus A (RVA) was detected by quantitative reverse transcription PCR (qRT-PCR) in 28 out of 91 (30.8%) lungs obtained from conventionally reared pigs with respiratory signs. Among the positive cases, intensive RVA signals were mainly localized in alveolar macrophages (