AUTHOR=Sakr Shimaa A. , EL-Emam Huda A. , Naiel Mohammed A. E. , Wahed Noha M. , Zaher Hanan A. , Abougabal Mohammed Sh. , Alghamdi Youssef S. , Albogami Sarah , Soliman Mohamed Mohamed , Shukry Mustafa , Elghareeb Mona M. 

TITLE=The Impact of Paulownia Leaves Extract on Performance, Blood Biochemical, Antioxidant, Immunological Indices, and Related Gene Expression of Broilers

JOURNAL=Frontiers in Veterinary Science

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.882390

DOI=10.3389/fvets.2022.882390

ISSN=2297-1769

ABSTRACT=<p>The current research sought to assess the effects of paulownia leaves extract (PLE) on performance, blood hematological, antioxidant activity, and immunological response of broiler chicken. In total, two hundred 1-day-old male <italic>Cobb</italic><sup>500</sup> chicks were allocated randomly into four equal treatments with 5 replicates. The first treatment served as a control (CNT) and was fed the basal diet only, while the other treated treatments were fed on the basal diet supplemented with 0.1, 0.3, and 0.5 g/kg diet of PLE, respectively. The performance results showed significant increments (<italic>P</italic> &lt; 0.05) in live body weight (LBW), weight gain (WG), and European production efficiency factors (EPEIs) (linearly; <italic>p</italic> &lt; 0.001) in cooperated with increasing PLE levels in broiler diets. At the same time, feed conversion ratio (FCR) and livability percentages were numerically enhanced under the effects of PLE supplementation. Moreover, a notable increase (<italic>P</italic> &lt; 0.05 or 0.01) in oxidative remarks activity (GSH, glutathione; SOD, super oxide-dismutase and CAT, catalase) and elevated levels of immunoglobulin (IgM, immunoglobulin M and IgG, immunoglobulin G) were noted (<italic>P</italic> &lt; 0.05) for treatments fed with PLE in a dose-dependent manner. Also, a dramatic linear increase was observed in <italic>mRNA</italic> expression of <italic>IGF-1, GHR, IL-1</italic>β, and <italic>IL-10</italic> genes of broiler chickens. This study concluded that enriched broiler feeds with 0.5 g/kg PLE might be a beneficial strategy to promote broiler health and production.</p>