AUTHOR=Choi Dong Hyeok , Ahn So Hyun , Park Kwangwoo , Choi Sang Hyun , Kim Jin Sung 

TITLE=Development of Total Lymphoid Irradiation (TLI)-Dedicated Shielding and Image-Guided System and Dose Evaluation Using 3D-Printed Rat Phantom

JOURNAL=Frontiers in Veterinary Science

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.832272

DOI=10.3389/fvets.2022.832272

ISSN=2297-1769

ABSTRACT=<sec><title>Purpose</title><p>The purpose of this study is to propose a technique for delivering accurate doses in an image-guided system by developing an experimental setup optimized for total lymphoid irradiation (TLI) in rat lung transplantation.</p></sec><sec><title>Materials and Methods</title><p>In this study, a position-controlled shielding system was developed, and the dose was quantitatively evaluated using a 3D rat phantom and Gafchromic EBT3 film. In addition, we made our own image-guided system that allows the position of the rat and the shielding system to be confirmed during TLI.</p></sec><sec><title>Results</title><p>As a result of using the position-controlled shielding system, it was found that the doses to the head and lungs were reduced by 93.1 and 87.4%, respectively, of the prescribed doses. In addition, it was shown that the position of the shielding system can be easily confirmed by using the image guidance system.</p></sec><sec><title>Conclusion</title><p>A shielding apparatus that can control dose delivery according to the size of the rat can optimize the dose for TLI in rat lung transplantation.</p></sec>