AUTHOR=Fernández Rivas Cristina , Porphyre Thibaud , Chase-Topping Margo E. , Knapp Charles W. , Williamson Helen , Barraud Olivier , Tongue Sue C. , Silva Nuno , Currie Carol , Elsby Derek T. , Hoyle Deborah V. TITLE=High Prevalence and Factors Associated With the Distribution of the Integron intI1 and intI2 Genes in Scottish Cattle Herds JOURNAL=Frontiers in Veterinary Science VOLUME=8 YEAR=2021 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2021.755833 DOI=10.3389/fvets.2021.755833 ISSN=2297-1769 ABSTRACT=
Integrons are genetic elements that capture and express antimicrobial resistance genes within arrays, facilitating horizontal spread of multiple drug resistance in a range of bacterial species. The aim of this study was to estimate prevalence for class 1, 2, and 3 integrons in Scottish cattle and examine whether spatial, seasonal or herd management factors influenced integron herd status. We used fecal samples collected from 108 Scottish cattle herds in a national, cross-sectional survey between 2014 and 2015, and screened fecal DNA extracts by multiplex PCR for the integrase genes