AUTHOR=Zhao Dengshuai , Yang Bo , Yuan Xingguo , Shen Chaochao , Zhang Dajun , Shi Xijuan , Zhang Ting , Cui Huimei , Yang Jinke , Chen Xuehui , Hao Yu , Zheng Haixue , Zhang Keshan , Liu Xiangtao TITLE=Advanced Research in Porcine Reproductive and Respiratory Syndrome Virus Co-infection With Other Pathogens in Swine JOURNAL=Frontiers in Veterinary Science VOLUME=8 YEAR=2021 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2021.699561 DOI=10.3389/fvets.2021.699561 ISSN=2297-1769 ABSTRACT=

The porcine reproductive and respiratory syndrome virus (PRRSV) is the pathogen causing epidemics of porcine reproductive and respiratory syndrome (PRRS), and is present in every major swine-farming country in the world. Previous studies have demonstrated that PRRSV infection leads to a range of consequences, such as persistent infection, secondary infection, and co-infection, and is common among pigs in the field. In recent years, coinfection of PRRSV and other porcine pathogens has occurred often, making it more difficult to define and diagnose PRRSV-related diseases. The study of coinfections may be extremely suitable for the current prevention and control in the field. However, there is a limited understanding of coinfection. Therefore, in this review, we have focused on the epidemiology of PRRSV coinfection with other pathogens in swine, both in vivo and in vitro.