AUTHOR=Su Mingjun , Chen Yaping , Qi Shanshan , Shi Da , Feng Li , Sun Dongbo 

TITLE=A Mini-Review on Cell Cycle Regulation of Coronavirus Infection

JOURNAL=Frontiers in Veterinary Science

VOLUME=7

YEAR=2020

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2020.586826

DOI=10.3389/fvets.2020.586826

ISSN=2297-1769

ABSTRACT=<p>Coronaviruses are widespread in nature and infect humans, mammals and poultry. They cause harm to humans and animals. Virus-mediated cell cycle arrest is an essential strategy for viral survival and proliferation in the host cells. A clarification system of the mechanisms of virus-induced cell cycle arrest is highly desirable to promote the development of antiviral therapies. In this review, molecular mechanisms of coronavirus-induced cell cycle arrest were systematically summarized. Moreover, the common features of coronavirus-mediated cell cycle arrest were discussed. This review will provide a theoretical basis for further studies on the infection mechanisms and prevention of coronaviruses.</p>