AUTHOR=Liu Zhi-guo , Wang Li-jun , Piao Dong-ri , Wang Miao , Liu Ri-hong , Zhao Hong-yan , Cui Bu-yun , Jiang Hai TITLE=Molecular Investigation of the Transmission Pattern of Brucella suis 3 From Inner Mongolia, China JOURNAL=Frontiers in Veterinary Science VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2018.00271 DOI=10.3389/fvets.2018.00271 ISSN=2297-1769 ABSTRACT=

Brucellosis is an endemic disease in China affecting both humans and livestock. The aim of the present study was to analyze two Brucella strains isolated from sheep spleens from Ulanqab in Inner Mongolia, China using classical and molecular typing techniques. The two strains were identified as Brucella suis biovar 3 and were closely related to isolates previously obtained from two different hosts (human and swine) in Guangxi Province. Our results suggest that B. suis can be directly or indirectly transferred from swine to sheep, which act as reservoirs for B. suis infection and later transmitted to humans. Multiple locus variable-number tandem repeat analysis (MLVA) is a useful tool for tracing the geographical origin of brucellosis infections and elucidating its transmission patterns.