AUTHOR=Skulberg Ragnhild , Cortellini Stefano , Chan Daniel L. , Stanzani Giacomo , Jepson Rosanne E. TITLE=Description of the Use of Plasma Exchange in Dogs With Cutaneous and Renal Glomerular Vasculopathy JOURNAL=Frontiers in Veterinary Science VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2018.00161 DOI=10.3389/fvets.2018.00161 ISSN=2297-1769 ABSTRACT=
Cutaneous and renal glomerular vasculopathy (CRGV) is a rare disease affecting dogs, with a recent apparent increase in prevalence since 2012 in the UK. This disease is characterized by a vasculopathy affecting small vessels of the kidney and skin, leading to thrombotic microangiopathy. The underlying etiology remains unknown although clinicopathological and histological findings resemble features of certain forms of thrombotic microangiopathy in people, for which plasma exchange (PEX) is considered an important component of therapy. The objective of the present study is to describe the use of PEX as adjunctive treatment in dogs diagnosed with CRGV. A retrospective review of dogs diagnosed with CRGV between 2014 and 2016 treated with PEX was performed. Clinical records were reviewed and data relating to signalment, diagnostic tests and management strategies were summarized. Information and complications relating to PEX were recorded. Six dogs were diagnosed with CRGV (