AUTHOR=Zheng Shaokai , Amado Pedro , Kiss Bernhard , Stangl Fabian , Haeberlin Andreas , Sidler Daniel , Obrist Dominik , Burkhard Fiona , Clavica Francesco TITLE=Quantitative Evaluation of Encrustations in Double-J Ureteral Stents With Micro-Computed Tomography and Semantic Segmentation JOURNAL=Frontiers in Urology VOLUME=2 YEAR=2022 URL=https://www.frontiersin.org/journals/urology/articles/10.3389/fruro.2022.836563 DOI=10.3389/fruro.2022.836563 ISSN=2673-9828 ABSTRACT=

Accurate evaluation of stent encrustation patterns, such as volume distribution, from different patient groups are valuable for clinical management and the development of better stents. This study quantitatively compares stent encrustation patterns from stone and kidney transplant patients. Twenty-seven double-J ureteral stents were collected from patients with stone disease or who underwent kidney transplantation. Encrustations on stent samples were quantified by means of micro−Computed Tomography and semantic segmentation using a Convolutional Neural Network model. Luminal encrustation volume per stent unit was derived to represent encrustation level, which did not differ between patient groups in the first six weeks. However, stone patients showed higher encrustation levels over prolonged indwelling times (p = 0.02). Along the stent shaft body, the stone group showed higher encrustation levels near the ureteropelvic junction compared to the ureterovesical junction (p = 0.013), whereas the transplant group showed no such difference. Possible explanations were discussed regarding vesicoureteral reflux. In both patient groups, stent pigtails were more susceptible to encrustations, and no difference between renal and bladder pigtail was identified. The segmentation method presented in this study is also applicable to other image analysis tasks in urology.