Skip to main content

REVIEW article

Front. Tuberc
Sec. Immunological Basis of Tuberculosis
Volume 2 - 2024 | doi: 10.3389/ftubr.2024.1487793
This article is part of the Research Topic Immune Response in Tuberculosis with Comorbidities or Coinfections View all 4 articles

Intersecting Epidemics: Deciphering the Complexities of Tuberculosis-Diabetes Comorbidity

Provisionally accepted
Mariana Araújo-Pereira Mariana Araújo-Pereira 1Caian Vinhaes Caian Vinhaes 2Beatriz Barreto Duarte Beatriz Barreto Duarte 1Klauss Villalva Klauss Villalva 3Artur Trancoso Lopo De Queiroz Artur Trancoso Lopo De Queiroz 1Bruno Bezerril Andrade Bruno Bezerril Andrade 1*
  • 1 Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil
  • 2 Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil
  • 3 Salvador University, Salvador, Bahia, Brazil

The final, formatted version of the article will be published soon.

    Within the global health landscape, tuberculosis (TB) presents an ongoing challenge, demanding innovative strategies for its control. This review spotlights the intersection of TB with diabetes mellitus (DM), recognized by the World Health Organization as a key risk factor in the TB epidemic. Particularly prevalent in low and middle-income nations, the TB-DM comorbidity drives up TB rates through a nexus of chronic inflammation. By delving into the epidemiological, clinical, and inflammatory dimensions, we elucidate the impact of TB-DM on patient prognosis and the multifaceted complications it introduces to disease transmission, diagnosis, and treatment protocols. Our synthesis aims to offer a fresh lens on TB-DM, fostering a nuanced understanding that could inform future healthcare policies and interventions.

    Keywords: Tuberculosis, Diabetes Mellitus, Epidemiology, Inflammation, multi-omics

    Received: 28 Aug 2024; Accepted: 29 Nov 2024.

    Copyright: © 2024 Araújo-Pereira, Vinhaes, Duarte, Villalva, Queiroz and Andrade. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Bruno Bezerril Andrade, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.