AUTHOR=Kodama Chiori , El Rifay Amira S. , Badra Rebecca , Abu Salbi Rana , Abubakar Abdinasir , Kayali Ghazi TITLE=Operationalizing One Health: strategic guidance for prevention and control of emerging and re-emerging vector-borne and zoonotic diseases in the Eastern Mediterranean Region JOURNAL=Frontiers in Tropical Diseases VOLUME=Volume 4 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/tropical-diseases/articles/10.3389/fitd.2023.1237688 DOI=10.3389/fitd.2023.1237688 ISSN=2673-7515 ABSTRACT=Operationalizing global One Health strategies at the field level to prevent and control vector-borne and zoonotic diseases (VBZDs) is of significant public health importance. Such strategies should be coordinated at the human-animal-ecosystems interface and applied at the national, regional, and global levels through the enforcement of effective policies. We aimed to develop a regional framework that can aid countries of the World Health Organization Eastern Mediterranean region to better prevent, detect, and respond to VBZDs events. This strategic guidance is a twelve-element framework drafted using various guidance documents and peer-reviewed scientific literatures, incorporating recommendations made through expert consultations. The framework elements were then integrated within a logical framework designed for practical implementation of One Health at regional and country level.